glutamic acid/zápal

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Polysaccharidic esters of N-derivatives of glutamic acid

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FIELD OF THE INVENTION The present invention relates to new products, namely polysaccharidic esters of N-derivatives of glutamic acid (N-GA). Their use as antiproliferatives in pharmaceutics is herein described. PRIOR ART Several modified polysaccharides have been described in the art. They are

Methods for treating joint pain using poly-gamma-glutamic acid

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FIELD OF THE INVENTION This invention relates to methods for treating joint pain associated with inflammatory, degenerative and other joint diseases. BACKGROUND OF THE INVENTION Over 20 million people in the United States suffer from degenerative joint diseases. This results in over 2 million

Pharmaceutical composition for preventing or treating Th17-mediated disease comprising poly-gamma-glutamic acid

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CROSS-REFERENCES TO RELATED APPLICATION This patent application claims the benefit of priority from Korean Patent Application No. 2012-0037414, filed on Apr. 10, 2012 in the Korean Intellectual Property Office (KIPO), the entire contents of which are incorporated herein by reference. BACKGROUND OF

Derivatives of aspartic acid and glutamic acid having anticholecystokinin activity

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This invention relates to amino acid derivatives, and more particularly to amino acid derivatives which possess anti-cholecystokinin activity. The invention also relates to methods for preparing such cholecystokinin antagonists and to compounds which are useful as intermediates in such

Hyaluronidase inhibitor containing poly-gamma-glutamic acid as an effective component

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CROSS-REFERENCE TO RELATED APPLICATIONS This application is filed under the provisions of 35 U.S.C. .sctn.371 and claims the priority of International Patent Application No. PCT/KR2005/003632 filed on 31 Oct. 2005 entitled "Hyaluronidase Inhibitor Containing Poly-Gamma-Glutamic Acid As An Effective

Method for synthesizing ramalin and ramalin precursor by using glutamic acid derivative and hydroxy aniline or hydroxy aniline having protected hydroxy group

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CROSS-REFERENCE TO RELATED APPLICATIONS This application is a U.S. national phase under the provisions of 35 U.S.C. .sctn.371 of International Patent Application No. PCT/KR12/02189 filed Mar. 26, 2012, which in turn claims priority of Korean Patent Application No. 10-2012-00069366 filed Jan. 19,

Peptides which stimulate the expression of the cytokines of inflammation and promote tissue regeneration

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FIELD OF THE INVENTION This invention concerns a new family of peptide molecules having the capacity especially of stimulating the expression of the cytokines of inflammation and promoting regeneration of tissues. The invention, thus, also pertains to pharmaceutical compositions containing at least

Muramyl compounds for treatment of septic shock

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This invention relates to the treatment and prophylaxis of sepsis, septic shock and other life-threatening inflammatory conditions. The mortality of systemic bacterial infection (bacteraemia) is high, particularly for gram-negative infections, where mortality levels are still comparable to those of

Inhibition of abnormal cell growth with corticotropin-releasing hormone analogs

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FIELD OF THE INVENTION The invention generally relates to treatments for abnormal cell proliferation, particularly for treating epidermal disorders, and more particularly relates to a method of inhibiting abnormal cell growth with the use of certain corticotropin-releasing hormone ("CRH") analogs.

Inhibition of abnormal cell growth with corticotropin-releasing hormone analogs

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Engineered botulinum neurotoxin

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BACKGROUND OF THE INVENTION Clostridium botulinum produces seven different neurotoxins (BoNTs) which differentiated serologically by the lack of anti-serum cross serotype neutralization. BoNTs are the most potent toxins known to humans and are the causative agents of the disease botulism (1). BoNTs

Orally administered small peptides synergize statin activity

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FIELD OF THE INVENTION This invention relates to the field of atherosclerosis. In particular, this invention pertains to the identification of a class of peptides that are orally administrable and that ameliorate one or more symptoms of atherosclerosis. BACKGROUND OF THE INVENTION Cardiovascular

Method for preparing ramalin

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CROSS-REFERENCE TO RELATED APPLICATIONS This application is a U.S. national phase under the provisions of 35 U.S.C. .sctn.371 of International Patent Application No. PCT/KR11/05206 filed Jul. 14, 2011, which in turn claims priority of Korean Patent Application No. 10-2010-0067710 filed Jul. 14,

Amide derivatives of p-isobutyl-phenyl-propionic acids and related pharmaceutical compositions

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The present invention relates to amide derivatives of p-isobutyl-phenyl-propionic acid, having general formula: ##STR2## wherein X represents the radical of a substituted amine selected amongst lysine, metatrifluorotoluidine, glutamic acid and aspartic acid. The anti-inflammatory properties of

Glycopeptide compositions

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FIELD OF THE INVENTION The present invention relates to glycopeptide compositions containing a glycoside and a peptide and their uses as biomaterials. Specific embodiments relate to chitosan-based glycopeptides. More specific embodiments relate to glycopeptides including chitosan and poly(amino

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