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glutamic acid/zhubný nádor
Odkaz sa uloží do schránky
Strana 1 od 54 výsledky
Method for treating cervical intraepithelial neoplasia using poly-gamma- glutamic acid
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TECHNICAL FIELD
The present invention relates to a method for treating cervical intraepithelial neoplasia using poly-gamma-glutamic acid, and more particularly, to a method for treating cervical intraepithelial neoplasia, comprising administering to a patient with cervical intraepithelial neoplasia
N-[N-(tetrahydropyrido[2,3-D]pyrimidinylmethyl)-aminomethylbenzo yl]glutamic acid derivatives as neoplastic growth inhibitors
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The present invention pertains to the individual diastereomers and to the diastereomeric mixture of glutamic acid derivatives of the formula: ##STR1## in which:
R.sup.1 is hydrogen, alkyl of 1 to 6 carbon atoms, or alkanoyl of 1 to 6 carbon atoms;
R.sup.2 is hydrogen or a carboxy protecting
Polysaccharidic esters of N-derivatives of glutamic acid
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FIELD OF THE INVENTION
The present invention relates to new products, namely polysaccharidic esters of N-derivatives of glutamic acid (N-GA). Their use as antiproliferatives in pharmaceutics is herein described.
PRIOR ART
Several modified polysaccharides have been described in the art. They are
Adjuvant composition containing poly-gamma-glutamic acid-chitosan nanoparticles
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TECHNICAL FIELD
The present invention relates to an adjuvant composition containing poly-gamma-glutamic acid-chitosan nanoparticles and a vaccine composition containing the adjuvant composition, and more particularly to an adjuvant composition containing nanoparticles prepared by ionic bonding
Derivatives of aspartic acid and glutamic acid having anticholecystokinin activity
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This invention relates to amino acid derivatives, and more particularly to amino acid derivatives which possess anti-cholecystokinin activity. The invention also relates to methods for preparing such cholecystokinin antagonists and to compounds which are useful as intermediates in such
Pyrimidinyl-glutamic acid derivatives
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BACKGROUND OF THE INVENTION
The folic acid antimetabolites aminopterin and amethopterin (also known as 10-methylaminopterin or methotrexate) are antineoplastic agents. These compounds inhibit enzymatic conversions involving metabolic derivatives of folic acid. Amethopterin, for example, inhibits
Mini-gastrin analogue, in particular for use in CCK2 receptor positive tumour diagnosis and/or treatment
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BACKGROUND OF THE INVENTION
Field of the Invention
The present invention relates to a mini-gastrin analogue and to its use in CCK2 receptor positive tumor diagnosis and/or treatment.
G protein-coupled receptors (GPCR) are used as target proteins for radiolabelled peptides since the early 90's. The
N-(4-(1-hydroxy-3-(5 ,6,7,8-tetrahydropyrido(2,3,-d)-pyrimidin-6-yl)prop-2-yl)benzoyl)glutamic acid derivatives
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The present invention pertains to the individual diastereomers and to the diastereomeric mixture of glutamic acid derivatives of the formula: ##STR1## in which: R.sup.1 is --OH or --NH.sub.2 ;
R.sup.2 is hydrogen or a carboxy protecting group;
R.sup.3 is hydrogen or a hydroxy protecting
Conjugates of D-glutamic acid: D-lysine copolymer and certain biochemicals
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BACKGROUND OF THE INVENTION
D-GL (D-glutamic acid:D-lysine copolymer) conjugates have been described at considerable length and various applications of D-GL conjugates of various immunologically reactive species have been reported. The following U.S. Pat. Nos. describe in considerable detail the
Producing highly specific, low cross-reactive antibody by immunizing with copolymer of D-glutamic acid and lysine
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FIELD OF ART
This invention relates to an improved antibody, antiserum containing such antibody and clone for the production of such an antibody and also relates to their production. This invention further relates to a method of immunoassay using such antibody or antiserum.
PRIOR ART
For example,
L-glutamic acid derivatives
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This invention pertains to derivatives of L-glutamic acid which are antineoplastic agents, to their preparation and use, and to intermediates useful in their preparation.
BACKGROUND OF THE INVENTION
The folic acid antimetabolites aminopterin and amethopterin (also known as 10-methylaminopterin or
L-glutamic acid derivatives
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Prihlásiť Registrácia
This invention pertains to derivatives of L-glutamic acid which are antineoplastic agents, to their preparation and use, and to intermediates useful in their preparation.
BACKGROUND OF THE INVENTION
The folic acid antimetabolites aminopterin and amethopterin (also known as 10-methylaminopterin or
L-glutamic acid derivatives
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Prihlásiť Registrácia
This invention pertains to derivatives of L-glutamic acid which are antineoplastic agents, to their preparation and use, and to intermediates useful in their preparation.
BACKGROUND OF THE INVENTION
The folic acid antimetabolites aminopterin and amethopterin (also known as 10-methylaminopterin or
Glutamic acid derivatives
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FIELD OF THE INVENTION
This invention concerns substituted glutamic acids and their composition and use. In particular, it concerns pyrimidylalkoxybenzoyl glutamic acids, acid esters and salts, processes and intermediates for their preparation, pharmaceutical formulations containing them, and their
Substituted glutamic acids
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FIELD OF THE INVENTION
This invention concerns substituted glutamic acids and their composition and use. In particular, it concerns pyrimidylalkylthiobenzoyl glutamic acids, acid esters and salts, processes and intermediates for their preparation, pharmaceutical formulations containing them, and
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