hyperalgesia/nauzea

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Comparison of Ultrasound Guided Genicular Nerve Block and Periarticular Infiltration in Knee Arthroplasty

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Total knee arthroplasty (TKA), one of the most commonly performed operations in orthopaedic department, has been a successful intervention for patients with end-stage knee arthritis. Rehabilitation after total knee arthroplasty (TKA) routinely starts immediately after surgery on the postoperative

Wound Infiltration With Tramadol, Dexmedetomidine, or Magnesium Plus Ropivacaine for Pain Relief After Spine Surgery

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Each participant will receive standard monitoring (ECG, SpO2, capnography, SBP, oesophageal temperature) and intravenous access will be established. A standard anesthesia protocol will be applied involving propofol 2mg/kg (iv) and remifentanil in TCI (target-controlled infusion). Cis-atracurium 0.2

Safety Profile of PETALO CVS in the Treatment of Non-thrombotic Internal Jugular Vein Stenosis and Chronic Headache

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Chronic headache is a disabling neurologic condition that affects 2-3 % of the general population. According to Headache Classification Committee of the International Headache Society, the chronic headache is defined as of at least one headache episode for 15 days a month, with at least eight days a

Ibuprofen and Erector Spinae Plane Block After Laparoscopic Sleeve Gastrectomy

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Bariatric surgery has been widely used in the treatment of obesity in recent years. Laparoscopic sleeve gastrectomy (LSG) is defined as the first-step bariatric surgery for patients in the high surgical risk group. It has been shown that the laparoscopic approach has lower complication rates,

Efficacy and Safety of Nerivio Device for Acute Treatment of Migraine in People With Chronic Migraine

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This open label study includes up to four visits. The enrollment and application training may occur in two separate visits instead of one. First visit - The first visit will include screening, enrollment and training on the application. Enrollment: The screening process will include an eligibility

Pre-hospital Nebulized Ketamine for Pain

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Ketamine is a non-competitive N-methyl-D-aspartate (NMDA)/glutamate receptor complex antagonist that decreases pain by diminishing central sensitization, hyperalgesia, and "wind-up" phenomenon at the level of the spinal cord (dorsal ganglion) and central nervous system Ketamine administration in

CandeSpartan Study. Candesartan Spanish Response-prediction and Tolerability Study

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CandeSpartan Study Candesartan Spanish Response-prediction and Tolerability study Observational study on response predictors and tolerability of Candesartan in usual clinical practice INTRODUCTION: Migraine is a neurological disease with a prevalence of 14% of the population 1, 2. It is the second

The Efficacy, Acceptability, Tolerability and Feasibility of a Therapeutic Virtual Reality Application

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Rationale: 21,2% of the Dutch population is suffering from chronic low-back pain. 90% of these patients suffers from chronic low-back pain not attributable to a recognisable, specific pathology (non-specific low-back pain). 30-40% of all patients suffering from chronic pain visit their GP for

Total Knee Replacement TIVA With Robotic Arm Assisted

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Preoperative Care Patients will be approached at the preadmission clinic or in the general ward before operation. The anaesthetic techniques will be explained and s/he will be recruited into the study if s/he agrees. Fasting will start 6 hours before surgery for solids and 2 hours clear fluid. All

Ultrasound-Guided Erector Spinae Plane Block Following Laparoscopic Sleeve Gastrectomy Surgery

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Prospective, Randomized Study Bariatric surgery has been widely used in the treatment of obesity in recent years. It has been shown to be effective in reaching the ideal weight and reducing obesity-induced comorbidities. Laparoscopic sleeve gastrectomy (LSG) is defined as the first-step bariatric

Investigation of the Strategy of Preventing Post-operative Opioid-induced Hyperalgesia

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1. After obtaining informed consent, patients will be randomized into two groups. 2. All patients receive remifentanil-propofol based TIVA and Bispectral index (BIS) monitor during breast surgery. In the end of surgery, intravenous NSAID(keto) 30mg and local anestehsia (Marcaine) infiltration around

Effect of Perioperative Intravenous Lidocaine Infusion in Robotic-Assisted Urologic Surgery

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In recent years, the risk of opioids in the post-operative period has gained interest due to the growing epidemic of addiction, dependence, and overdose. The rate of drug overdose secondary to opioids has continued to increase at an alarming rate. This has been a primary point of concern in all

Effects of an Opioid Sparing Care Pathway for Patients Undergoing Obesity Surgery

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Aim To evaluate the effects of opioid sparing care pathways compared to conventional opioid-based treatment for pain relief, opioid consumption, recovery after surgery, self-efficacy and health economy in patients undergoing obesity surgery. The aim will be investigated by a prospective, randomized,

Cannabis Oil for Pain in Parkinson's Disease

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BACKGROUND AND RATIONALE Pain is a common symptom in PD and is reported in up to 50 % of patients. Pain in PD has been classified as musculoskeletal, dystonic (particularly in OFF-periods), radicular and central pain, and is frequently associated with muscle rigidity, postural abnormalities and

The Effect of Perioperative Intravenous Lidocaine Infusion on Opioid Consumption After Lumbar Spine Surgery

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Lidocaine has analgesic and anti-inflammatory effects. It has been shown to reduce early postoperative pain and nausea. Additionally, lidocaine has been shown to have positive effects in the recovery of bowel function, with a reduction in time to first flatus, first bowel sounds, first bowel

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