hyperglycemia/obezita

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Maternal glucose at 28 weeks of gestation is not associated with obesity in 2-year-old offspring: the Belfast Hyperglycemia and Adverse Pregnancy Outcome (HAPO) family study.

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OBJECTIVE Diabetes during pregnancy is a strong risk factor for obesity in the offspring, but the age at which this association becomes apparent is unknown. The purpose of this study was to examine the relation of glycemia during pregnancy with anthropometry in offspring of nondiabetic pregnant

Effects of high glucose on vascular endothelial growth factor synthesis and secretion in aortic vascular smooth muscle cells from obese and lean Zucker rats.

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Type 1 diabetes is characterized by insulin deficiency, type 2 by both insulin deficiency and insulin resistance: in both conditions, hyperglycaemia is accompanied by an increased cardiovascular risk, due to increased atherosclerotic plaque formation/instabilization and impaired collateral vessel

Characterization of Nob3, a major quantitative trait locus for obesity and hyperglycemia on mouse chromosome 1.

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New Zealand obese (NZO) mice present a metabolic syndrome of obesity, insulin resistance, and diabetes. To identify chromosomal segments associated with these traits, we intercrossed NZO mice with the lean and diabetes-resistant C57BL/6J (B6) strain. Obesity and hyperglycemia in the (NZO x B6)F2

Combination of obesity with hyperglycemia is a risk factor for the presence of vertebral fractures in type 2 diabetic men.

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Although patients with type 2 diabetes show no bone mineral density (BMD) reduction, fracture risks are known to increase. It is unclear why the patients have an increased risk of fracture despite sufficient BMD. We investigated the relationships of body mass index (BMI), HbA(1c), and urinary

[Relationship between abdominal obesity/pre-obesity and hyperglycemia in postmenopausal women].

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OBJECTIVE To explore the relationship between abdominal obesity/pre-obesity and hyperglycemia in postmenopausal women. METHODS A total of 323 women aged than 35 years or older and with natural menopause more than 12 months were selected from Suzhou Industrial Park in 2014 community comprehensive

Ethanol-induced hypothermia and hyperglycemia in genetically obese mice.

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Blood glucose and rectal temperatures were monitored in two strains of genetically obese mice (C57 BL/6J ob/ob) prior to and following intragastric ethanol administration in an attempt to relate the hypothermic response to ethanol to extracellular glucose concentration. In contrast to expectation,

Sleep duration and hyperglycemia among obese and nonobese children aged 3 to 6 years.

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OBJECTIVE To investigate the association between sleep duration and risk of hyperglycemia among preschool Chinese children. METHODS A population-based cross-sectional study. METHODS Seventy-one randomly selected kindergartens in Tianjin, China. METHODS Six hundred nineteen obese (body mass index z

Age-dependent decline of association between obesity and hyperglycemia in men and women.

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OBJECTIVE The purpose of this study was to determine whether age influences the association between obesity and hyperglycemia. METHODS The subjects were 57,576 Japanese male and female workers aged 35-70 years. The associations of adiposity indices, including BMI, waist circumference, and

Hyperglycemia, maturity-onset obesity, and insulin resistance in NONcNZO10/LtJ males, a new mouse model of type 2 diabetes.

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As a new mouse model of obesity-induced diabetes generated by combining quantitative trait loci from New Zealand Obese (NZO/HlLt) and Nonobese Nondiabetic (NON/LtJ) mice, NONcNZO10/LtJ (RCS10) male mice developed type 2 diabetes characterized by maturity onset obesity, hyperglycemia, and insulin

[Effect of a high glucose load on serum concentrations of C-reactive protein and alpha1-antitrypsin in obese women].

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Obesity is associated with increased inflammation. C-reactive protein (CRP) is a proinflammatory molecule, and alpha1-antitrypsin is an inflammation-sensitive plasma protein. Proinflammatory process may be influenced by postprandial hyperglycemia. OBJECTIVE The aim of the present study was to

Hyperlipidemia, hyperglycemia and hypertension in repeatedly bred parents of the obese spontaneously hypertensive rat (obese/SHR) unaccompanied by arteriosclerosis.

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A sub-strain of male and female spontaneously hypertensive rats (SHR) capable of having massively obese or non-obese offspring were bred repeatedly or were maintained as virgin controls. When the male and female breeders had sired or given birth to 5 litters of young, they were autopsied along with

Aerobic or resistance exercise performed the previous day does not attenuate postprandial hyperglycemia-induced endothelial dysfunction in overweight/obese adults.

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Postprandial hyperglycemia (PPH) impairs vascular endothelial function (VEF). A single bout of aerobic exercise (AE) attenuates PPH-induced decreases in brachial artery flow-mediated dilation (FMD), a non-invasive measure of VEF, in healthy adults for up to 17 h post-exercise. Studies

Transplantation of pancreatic islets from hypothalamic obese rats corrects hyperglycemia of diabetic rats.

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Pancreatic islets isolated from adult obese rats, obtained by neonatal treatment with monosodium L-glutamate (MSG), oversecrete insulin stimulated by glucose concentration. Whereas adult MSG obese rats are hyperinsulinemic, their pancreatic islets still secrete insulin after high glucose demand.

Specific relation between abdominal obesity and early-phase hyperglycemia is modulated by hepatic insulin resistance in healthy older women.

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OBJECTIVE To describe the impact of abdominal obesity and hepatic insulin resistance on phase-specific glycemic responses in older women. METHODS We studied 23 healthy older women (60-88 years old). Abdominal obesity was defined by an abdominal circumference > or =95 cm. Plasma glucose and insulin

Relationship between beta-endorphin/beta-lipotropin, hyperglycemia, and hyperinsulinemia in obese male Zucker rats.

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The relationship between beta-endorphin(beta-EP)/beta-lipotropin(beta-LP) and insulin secretion in the basal state and after glucose challenge was studied in obese male Zucker rats and their lean littermates. Baseline plasma beta-EP/beta-LP concentrations were similar in the two groups of animals.

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