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Benzoimidazole derivatives and pharmaceutical composition comprising the same

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TECHNICAL FIELD The present invention relates, in general, to novel benzoimidazole derivatives and, more particularly, to novel benzoimidazole derivatives functioning as antagonists to a vanilloid receptor (capsaicin receptor; Transient Receptor Potential Channel, Vanilloid subfamily member 1;

Polynucleotides that encode the calcitonin gene-related peptide receptor coponent factor (HOUNDC44)

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FIELD OF THE INVENTION This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists

Modulation of substance P by compounds containing calcium sulfate and methods relating thereto

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TECHNICAL FIELD The present invention relates generally to a method of modulating substance P by compounds containing calcium sulfate, particularly syngenite, gorgeyite and gypsum, and more specifically, to the synthesis of such compounds as well as their use to treat a variety of conditions

Tetrazolyl-substituted quinuclidines as substance P antagonists

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TECHNICAL FIELD This invention relates to novel tetrazolyl-substituted quinuclidine compounds and their pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and the use of such compounds as substance P antagonists. BACKGROUND ART Substance P is a naturally

Protein free formula

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FIELD OF THE INVENTION The present invention relates to the stimulation of health in infants receiving an amino acid based formula. BACKGROUND OF THE INVENTION In a preferred situation, infants are breastfed by the mother. However, often in infants, after an initial period of being breast fed,

Benzyloxyquinuclidines as substance P antagonists

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BACKGROUND OF THE INVENTION This application is the U.S. national phase of PCT Patent Application PCT/JP94/01092, which was filed in the Japanese Receiving Office on Jul. 5, 1994. This invention relates to novel and useful benzyloxyquinuclidines of interest to those in the field of medical chemistry

Bi-pyridinyl derivatives as NK-1 antagonists

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PRIORITY TO RELATED APPLICATIONS This application claims the benefit of European Application No. 05101324.1, filed Feb. 22, 2005, which is hereby incorporated by reference in its entirety. BACKGROUND OF THE INVENTION Substance P is a naturally occurring undecapeptide belonging to the tachykinin

Methods of screening for agonists and antagonists of the interaction between the human KIAA0001 receptor and ligands thereof

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FIELD OF THE INVENTION This invention relates to methods for discovering agonists and antagonists of the interaction between UDP-sugars (e.g.,UDP-glucose, UDP-galactose, UDP-glucuronic acid, and UDP-N-acetyl glucosamine) and their cellular receptor, human KIAA0001 receptor. The invention also

Nucleic acid encoding a bovine calcitonin receptor-like receptor (BECRLR)

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FIELD OF THE INVENTION This invention relates to newly identified polypeptides and polynucleotides encoding such polypeptides, to their use in therapy and in identifying compounds that may be agonists or antagonists that are potentially useful in therapy, and to production of such polypeptides and

Naphthalenecarboxamides as tachykinin receptor antagonists

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BACKGROUND The mammalian neurokinins comprise a class of peptide neurotransmitters which are found in the peripheral and central nervous systems. The three principal neurokinins are Substance P (SP), Neurokinin A (NKA) and Neurokinin B (NKB). There are also N-terminally extended forms of at least

Substituted 1-piperidin-4-yl-4-azetidin-3-yl-piperazine derivatives and their use as neurokinin antagonists

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CROSS REFERENCE OT RELATED APPLICATIONS This application is the national stage of Application No. PCT/EP2003/051042, filed 17 Dec. 2003, which application claims priority from PCT/EP2002/14837 filed 23 Dec. 2002, which are hereby incorporated by reference. FIELD OF THE INVENTION This invention

Substituted 1-piperidin-4-yl-4-pyrrolidin-3-yl-piperazine derivatives and their use as neurokinin antagonists

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CROSS REFERENCE TO RELATED APPLICATIONS This nonprovisional patent application is the National Stage of International Application No.PCT/EP2003/051041, filed 17 Dec. 2003, which claims priority from PCT/EP2002/14831, filed 23 Dec. 2002, which are hereby incorporated by reference. FIELD OF THE

Substituted 1-piperidin-3-yl-4-piperidin-4-yl-piperazine derivatives and their use as neurokinin antagonists

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CROSS REFERENCE TO RELATED APPLICATIONS This application is the national stage of Application No. PCT/EP2003/051035, filed 17 Dec. 2003, which application claims priority from PCTEP2002/14835 filed 23 Dec. 2002, which are hereby incorporated by reference. FIELD OF THE INVENTION This invention

Biaryl benzoimidazole derivatives and pharmaceutical composition comprising the same

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TECHNICAL FIELD The present invention relates to a novel biaryl benzoimidazole derivative, a method for preparing the same, and a pharmaceutical composition comprising the same, in which the biaryl benzoimidazole derivative functions as an antagonist of the vanilloid receptor (Capsaicin receptor;

Benzimidazolone derivatives as CB2 receptor ligands

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BACKGROUND OF THE INVENTION This invention relates to benzimidazolone derivatives. These compounds have selective cannabinoid(CB)2 receptor binding activity. The present invention also relates to a pharmaceutical composition, method of treatment and use, comprising the above derivatives for the

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