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8 výsledky
Method of preventing emesis using tetrahydrobenz [CD]indole-6-carbonxamides
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BACKGROUND OF THE INVENTION
This invention provides a method of preventing emesis and in mammals as well as formulations suitable therefor.
Extensive research has been conducted for a number of years directed toward the development of compounds capable of preventing emesis and treating sexual
Indole derivatives in the treatment of emesis
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This invention relates to the use of certain indole derivatives in the treatment or prevention of emesis.
International Patent Application WO 92/06973 discloses a series of indole derivatives which are potent serotonin (5-HT.sub.1) agonists. These compounds are useful for treating disorders arising
Indole derivatives
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This invention relates to indole derivatives, to processes for their preparation, to pharmaceutical compositions containing them and to their medical use.
In particular the invention relates to compounds which are potent and selective antagonists of 5-hydroxytryptamine (5-HT) at 5-HT receptors of
Indole derivatives
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This invention relates to heterocyclic compounds, to processes for their preparation, to pharmaceutical compositions containing them and to their medical use. In particular the invention relates to compounds which act upon 5-hydroxytryptamine (5-HT) receptors of the type located on terminals of
Indole derivatives
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FIELD OF THE INVENTION
This invention relates to indole derivatives, to processes for their preparation and to pharmaceutical compositions comprising them.
In particular the invention relates to compounds which are selective antagonists of 5-hydroxytryptamine (5-HT) at 5-HT.sub.3
2-aryl indole derivative as antagonists of tachykinins
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This invention relates to indole derivatives and their use as tachykinin antagonists, and in particular as neurokinin-1 receptor antagonists.
We have now found a class of indole derivatives which are potent receptor antagonists of tachykinins, especially of the neurokinin-1 (substance P)
Ketone derivatives
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This invention relates to ketone derivatives, to processes for their preparation, to pharmaceutical compositions containing them and to their medical use. In particular the invention relates to compounds which act upon 5-hydroxytryptamine (5-HT) receptors of the type located on terminals of primary
Ketone derivatives
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This invention relates to ketone derivatives, to processes for their preparation, to pharmaceutical composition containing them and to their medical use. In particular the invention relates to compounds which act upon 5-hydroxytryptamine (5-HT) receptors of the type located on terminals of primary
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