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Strana 1 od 39 výsledky
Lectin-like domain of thrombomodulin and its therapeutic use
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RELATED APPLICATIONS
This application is the U.S. National Phase under 35 U.S.C. .sctn. 371 of International Application PCT/EP02/05727, filed May 24, 2002, which claims priority of EP 01201979.0, filed May 25, 2001 Each of the above applications are incorporated herein by reference in their
Methods of identifying anti-inflammatory compounds
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FIELD OF THE INVENTION
The present invention relates to methods of identifying compounds useful in treating an autoimmune disease. More specifically, the present invention relates to various methods of screening and selecting for compounds, such as IgG antibodies or biologically relevant fragments
Methods of identifying anti-inflammatory compounds
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FIELD OF THE INVENTION
The present invention relates to methods of identifying compounds useful in treating an autoimmune disease. More specifically, the present invention relates to various methods of screening and selecting for compounds, such as IgG antibodies or biologically relevant fragments
Factor D inhibitors useful for treating inflammatory disorders
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BACKGROUND
Complement Factor D is part of the alternative pathway of the complement cascade and plays an early and central role in activating the pathway. Complement Factor C3b is generated from complement component C3 by the C3 convertase enzyme, distinct forms of which are produced following
Peptide inhibitors of inflammation mediated by selectins
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BACKGROUND OF THE INVENTION
This invention is generally in the field of methods for the treatment and prevention of inflammatory responses using peptides derived from selectins.
The adherence of platelets and leukocytes to vascular surfaces is a critical component of the inflammatory response, and
Peptide inhibitors of inflammation mediated by selectins
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BACKGROUND OF THE INVENTION
This invention is generally in the field of methods of the treatment and prevention of inflammatory responses using peptides derived from selectins including GMP-140, ELAM-1, and lymphocyte-homing receptor.
The adherence of platelets and leukocytes to vascular surfaces is
Lectins and uses thereof
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FIELD OF THE INVENTION
The present invention relates to chemical compounds, methods for their discovery, and their therapeutic and research use. In particular, the present invention provides antiviral and antimicrobial lectin compounds and methods of their use.
BACKGROUND OF THE INVENTION
Acquired
Lectins as anti-fibrotic agents
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BACKGROUND
Lectins bind to carbohydrate moieties, e.g. acetylglucosamine, that are ubiquitous in the mammalian extracellular matrix. This suggests the possibility that lectins may be used to coat the matrix and limit further binding of collagen, elastin, and other connective tissue components to
Anti-inflammatory, tolerogenic and immunoinhibiting properties of carbohydrate binding-peptides
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is directed to methods for inhibiting immune responses or cellular interactions in mammals by the administration thereto of one or more lectin derived carbohydrate binding peptides. In particular, this invention is directed to
Anti-inflammatory, tolerogenic and immunoinhibiting properties of carbohydrate binding peptides
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is directed to methods for inhibiting immune responses or cellular interactions in mammals by the administration thereto of one or more lectin derived carbohydrate binding peptides. In particular, this invention is directed to
Anti-inflammatory, tolerogenic and immunoinhibiting properties of carbohydrate binding-peptides
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention is directed to methods for inhibiting immune responses or cellular interactions in mammals by the administration thereto of one or more lectin derived carbohydrate binding peptides. In particular, this invention is directed to
Markers for alternatively activated macrophages
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a continuation of PCT International Patent Application No. PCT/EP2004/052076, filed on Sep. 7, 2004, designating the United States of America, and published, in English, as PCT International Publication No. WO 2005/024418 A2 on Mar. 17,
Immunomodulating compositions and uses therefor
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FIELD OF THE INVENTION
THIS INVENTION relates generally to immunomodulating compositions. More particularly, the present invention is directed to compositions comprising an immune-modulating agent and a lectin-interactive agent, which are useful for stimulating and prolonging host immune cell
Human leukolectins and uses thereof
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The present invention relates to a polypeptide, namely a lectin, its encoding nucleic acid sequence and antibodies to the polypeptide and their use in various medical applications.
The cellular immune defence system is central to surviving microbial and parasitic challenges. This system is also most
Leukolectins and uses thereof
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The present invention relates to a polypeptide, namely a lectin, its encoding nucleic acid sequence and antibodies to the polypeptide and their use in various medical applications.
The cellular immune defense system is central to surviving microbial and parasitic challenges. This system is also most
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