Control Group:Benzydamine Hydrochloride spray by mouth three times daily for 20 days.
Follow up: The patients will be recalled at one week interval for 20 days.

Intervention group: 90% solcoseryl and 10% pumpkin seed oil spray by mouth three times daily for 20 days

Mucositis Oral

Patients will rinse by mouth three times daily for 20 days

Benzydamine Hydrochloride

Patients will receive by mouth three times daily for 20 days

Solcoseryl and pumpkin seed oil

Treatment of Chemotherapy and Radiotherapy Induced Oral Mucositis

Clinical Evaluation of Solcosreyl and Pumpkin Seed Oil Versus Benzydamine Hydrochloride in Management of Patients With Chemotherapy and Radiotherapy Induced Oral Mucositis

World Health Organization (WHO)scale.It is graded from 0 to 4. If the patient has no signs and symptoms, it is graded as 0. If the patient has painless ulcers, edema, or mild soreness, it is graded as 1. If there is painful erythema, edema, or ulcers but able to eat, it is graded as 2. If there is painful erythema, edema, or ulcers but unable eat, it is graded as 3. If there a requirement for parenteral or enteral support, it is graded as 4

Patient-Reported Oral Mucositis( PROMS scale) will measure Quality of life .The PROMS scale consists of 10, 100-mm horizontal visual analogue scales addressing oral functions affected by oral mucositis. Participants will be asked to mark a point on the line that best represents their present intra-oral condition.During the baseline examination and prior to their completion of the actual PROMS scale questionnaire, participants were subjected to a few training test-visual analogue scale questions focused on simple everyday topics to familiarize them with the concept of visual analogue scale assisted measurements. The participants will complete the PROMS questionnaire thrice; baseline, after the first week, and at the end of the study after the second week.

Ghada zaki

assistant lecturer at el ahram canadian university

Treatment will be placed in identical spray containers

50 volunteers on cross over design , receiving 4g/day of cis9,trans11 CLA

50 volunteers cross over design, placebo oil 4g/day

Cardiovascular Disease

Placebo oil

Rowett Institute of Nutrition and Health

Conjugated Linoleic Acid Supplementation Study

Effects of cis9,trans11 Conjugated Linoleic Acid on Platelet Function, Markers of Haemostasis and Inflammation on Humans

Using fluorescently-conjugated monoclonal antibodies and whole blood flow cytometry after ex vivo stimulation with adenosine diphosphate (ADP), thrombin receptor-activating peptide (TRAP) P-selectin expression as early marker of platelet activation Activated fibrinogen receptor as late marker of platelet activation

Using collagen-epinephrine coated cartridges Using collagen-adenosine diphosphate coated cartridges

Using semi-automated coagulometer using fibrinogen assay according to Clauss method

Using a Helena Platelet Aggregation Chromogenic Kinetics System-4 (PACKS-4) light transmission aggregometer

Using enzyme-linked immunoabsorbent assay (ELISA) in plasma

linoleic acid/hemorrhage

Treatment of Chemotherapy and Radiotherapy Induced Oral Mucositis

Conjugated Linoleic Acid Supplementation Study

Substrate Cycling in Energy Metabolism

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