Iron-deficiency

Only female participants are being studied

labeled ferrous fumarate

labeled iron as Ferrous Fumarate + galacto-oligosaccharides

labeled ferrous fumarate + prebiotics

labeled iron as Ferrous Sulfate + galacto-oligosaccharides

labeled ferrous sulfate + prebiotics

ETH Zurich

Effect of Prebiotics on Iron Absorption in Women With Low Iron Stores

Fractional iron absorption will be calculated based on the shift of the iron isotope ratios in the collected blood samples after the administration of several isotopically labelled iron supplements (days 0, 2 16, 18, 20, 37, 39, 41).Fractional iron absorption will be measured as erythrocyte incorporation of the naturally occurring iron forms with different masses used to label the iron supplements.

Prof. Michael B. Zimmermann

Head of Laboratory of Human Nutrition

Swiss Federal Institute of Technology

Antistress AG, Gesellschaft für Gesundheitsschutz - Burgerstein Vitamine

Prolardii GR Caps includes 4 strains of living lyophilized lactic bacteria (Lactobacillus rhamnosus GG, Bifidobacterium lactis B94, Lactobacillus casei 5773 and Lactobacillus acidophilus LA3), a yeast (Saccharomyces boulardii), a fructo-oligosaccharide (Actilight) and a dry extract of Inula helenium.

Antibiotic-associated Diarrhea

Prolardii: 2 capsules per day for 12 to 15 days

Prolardii

Placebo

ResearchLink

Prevention of Antibiotic-Associated Diarrhoea With Prolardii

Double-blind Randomised Placebo-controlled Study of Prolardii Gastro-resistant (GR) Caps in the Prevention and Treatment of Antibiotic-associated Diarrhoea.

Percentage of patients presenting an acute antibiotic-associated diarrhea

Percentage of patients showing solicited symptoms (flatulence, bloating, abdominal pain/cramps, nausea and/or vomiting)

Percentage of patients with adverse events

Therabel Pharma SA/NV

ECSOR

Double-blind parallel placebo-controlled randomized study

We prospectively will survey 30 nuns from the "Congregazione delle Suore Collegine della Santa Famiglia", Palermo, Italy. The subjects will be recruited between January 2017 and June 2017 and will be examined before and after the diet period (30 days) with ancient grains, undergoing clinical evaluation and blood and feces samples collection. Ancient wheat flours will be administered in open label for 30 days

Gluten Sensitivity

Ancient wheat flours will be administered in open label for 30 days

Ancient wheat flours

Congregazione delle Suore Collegine della Santa Famiglia

Effects of Ancient Grains-based Diet in a Closed Community

Laboratory Values evaluation at baseline and after a 30 days challenge with ancient grains-based diet.

Evaluation of modifications of intestinal microbiota (bacterial flora) by feces samples examination, before and after a 30 days challenge with ancient grains-based diet.

Evaluation of modifications in cytokines production from PBMC, before and after the diet period (30 days) with ancient grains.

oligosaccharide/nauzea

Effect of Prebiotics on Iron Absorption in Women With Low Iron Stores

Prevention of Antibiotic-Associated Diarrhoea With Prolardii

Effects of Ancient Grains-based Diet in a Closed Community

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