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oligosaccharide/zhubný nádor
Odkaz sa uloží do schránky
Strana 1 od 69 výsledky
Tumor specific oligosaccharide sequences and use thereof
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FIELD OF THE INVENTION
The present invention relates to oligosaccharide sequences, which are specifically expressed by human tumors. The present invention describes methods for the detection of the tumor specific oligosaccharide structures of the invention as well as methods for the production of
Tumor specific oligosaccharide epitopes and use thereof
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FIELD OF THE INVENTION
The present invention relates to oligosaccharide sequences, which are specifically expressed by human tumors. The present invention describes methods for the detection of the tumor specific oligosaccharide structures disclosed in the invention as well as methods for the
Detection of prostate and other cancers by assaying for cancer-specific antigens having linked oligosaccharides which are at least triantennary
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FIELD OF THE INVENTION
The present invention relates to the field of cancer immunoassays. Specifically, provided is an immunoassay method for detection of the prostatic-specific antigen (PSA). The immunoassay of the present invention distinguishes between normal prostatic-specific antigen and
Detection of prostate and other cancers by assaying for cancer-specific antigens having linked oligosaccharides which are at least triantennary
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FIELD OF THE INVENTION
The present invention relates to the field of cancer immunoassays. Specifically, provided is an immunoassay method for detection of the prostatic-specific antigen (PSA). The immunoassay of the present invention distinguishes between normal prostatic-specific antigen and
Methods of oligosaccharide profiling for the detection of cancer
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BACKGROUND OF THE INVENTION
Ovarian cancer is the fifth leading cause of death from cancer and has the highest mortality rate among the gynecologic malignancies in the United States. According to the American Cancer Society (2002), approximately 23,300 women will be diagnosed with ovarian cancer in
Cancer specific oligosaccharide sequences and use thereof
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FIELD OF THE INVENTION
The present invention relates to oligosaccharide sequences, which are specifically expressed by certain cancer cells, tumours and other malignant tissues. The present invention describes methods to detect cancer specific oligosaccharide sequences as well as methods for the
Antibodies, method of preparing same, oligosaccharides and clones for providing said antibodies, and the use of said antibodies for tumor diagnosis and therapy
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The invention relates to novel antibodies directed against the oligosaccharide portion of glycoproteins, methods of preparing said antibodies and oligosaccharide-haptens and clones for generating these antibodies. The novel antibodies are suited for tumor diagnosis and therapy as they are capable of
Monoclonal antibody which recognizes the oligosaccharide N-glycolylated-galactose-glucose sialic acid in malignant tumors, and composition containing it
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TECHNICAL SECTOR
The present invention is related with the field of immunology and human medicine particularly with the generation and selection of a monoclonal antibody (Mab) against the N-glycolylated-galactose-glucose sialic acid olygosaccharide sequence that can be used for the diagnosis and
Radiolabeled glucans which bind to leukocytes, sites of infection, inflammation, atherosclerosis, or cancer
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to radiodiagnostic agents and reagents for preparing such agents, and also methods for producing radiolabeled radiodiagnostic agents. Specifically, the invention relates to technetium-99m (.sup.99m Tc) labeled agents,
Monoclonal antibodies and vaccine development directed to human cancer-associated antigens by immunization with animal and human and with synthetic carbohydrate-carrier conjugates
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FIELD OF THE INVENTION
The present invention relates to new methods for the production of monoclonal antibodies specific to human cancer-associated antigens and to the hybridomas and monoclonal antibodies produced therefrom. More particularly, the present invention relates to new methods for the
Monoclonal antibodies and vaccine development directed to human cancer-associated antigens by immunization with animal and human mucin and with synthetic carbohydrate-carrier conjugates
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FIELD OF THE INVENTION
The present invention relates to new methods for the production of monoclonal antibodies specific to human cancer-associated antigens and to the hybridomas and monoclonal antibodies produced therefrom. More particularly, the present invention relates to new methods for the
Production of fucosyl antigens and antibodies for recognizing same determination of cancer associated carbohydrate linkage using same and kit for the determination
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TECHNICAL FIELD
The present invention relates to techniques for producing fucosyl antigens and antibodies for recognizing the same, and more particularly to a process for producing carbohydrate antigens containing a specific carbohydrate linkage as a hapten and a process for producing from the
Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
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FIELD OF INVENTION
The present invention is related to the field of vaccines and is particularly related to the development of novel glycoconjugation technologies which can be used to prepare glycoconjugates in which multi-oligosaccharides are covalently linked to the same carrier
Synthetic glycoamines and methods for their use that affect cell adhesion, inhibit cancer cell metastasis, and induce apoptosis
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FIELD OF THE INVENTION
The present invention relates to pharmaceuticals that affect cell adhesion, inhibit cancer cell metastasis, and induce apoptosis both in vitro and in vivo.
Background of the Invention
Cell adhesion is one important property that differentiates multi-cellular organisms from
Multi oligosaccharide glycoconjugate bacterial meningitis vaccines
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FIELD OF INVENTION
The present invention is related to the field of vaccines and is particularly related to the development of novel glycoconjugation technologies which can be used to prepare glycoconjugates in which multi-oligosaccharides are covalently linked to the same carrier
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