oral ulcer/hnačka

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Recurrent oral ulcers and diarrhea in a renal transplant patient. Behcet's disease (associated with IgA nephropathy) and acute tacrolimus nephrotoxicity.

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Neonatal Crohn's disease with Oral ulcer as the first symptom caused by a compound heterozygote mutation in IL-10RA: a case report.

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To investigate the clinical and genetic characteristics of neonatal Crohn's disease (CD), improve recognition of neonatal CD, and reduce the number of patients that are missed or misdiagnosed.

Methods

A 10-day-old Chinese girl with oral ulcers was

A rabbit model of diarrhea due to invasive Escherichia coli.

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A nonpiliated strain of invasive Escherichia coli of human origin (HInvEC) was given to rabbits (weight, 0.7-1.1 kg) in doses ranging from 1.5 X 10(8) to 2.5 X 10(10) bacteria. E. coli strain HInvEC colonized the ileum, cecum, and colon in large numbers for one to three days and produced diarrhea in

Tissue distribution of bovine viral diarrhea virus antigens in persistently infected cattle.

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The tissue distribution and cellular localization of viral antigens in three cattle with persistent bovine viral diarrhea virus (BVDV) infection was studied. In three cases, necropsy findings of oral ulcers, abmasal ulcers and necrosis of Peyer's patches were suspected have been caused by BVDV

Apremilast to treat oral ulcers in Behçet syndrome.

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Apremilast, an oral small molecule, is a phosphodiesterase 4 (PDE-4) blocker. It has been shown to be efficacious in managing psoriasis (PS) and psoriatic arthritis (PSA). In two controlled studies, it was also effective in controlling oral ulcers of Behçet syndrome (Bsy). The main side effects

Trial of Apremilast for Oral Ulcers in Behçet's Syndrome.

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The small-molecule phosphodiesterase 4 inhibitor apremilast modulates cytokines that are up-regulated in Behçet's syndrome. In a phase 2 trial involving patients with Behçet's syndrome, apremilast reduced the incidence and severity of oral ulcers. Data on the efficacy and safety of

Development and Improvement of Simple Colonic Mucosal Ulcer during Treatment of Severe Ulcerative Colitis with Tacrolimus.

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Diarrhea, melena, and lower abdominal pain developed in a male in his 20s and colonoscopy showed pancolitis-type severe ulcerative colitis (UC). Treatment was initiated with 4,000 mg of 5-aminosalicylic acid and 60 mg/day of prednisolone, but the symptoms and inflammatory reaction worsened with

The clinical, immunohematological, and molecular study of Iranian patients with severe congenital neutropenia.

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Severe congenital neutropenia (SCN) is a rareE primary immunodeficiency disorder characterized by early onset recurrent infections in association with persistent severe agranulocytosis. To identify the clinical, immunohematological, and molecular characteristics of patients with SCN, 18 Iranian

Multiple Small Intestine Ulcers with Desquamation of the Fingers.

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A 73-year-old female was admitted to our hospital with abdominal pain and diarrhea. Computed tomography detected distension of the small intestine. A palmar erythema, multiple oral ulcers, and desquamation of the fingers appeared after hospitalization. Small-bowel endoscopic images showed multiple

A delayed diagnosis of X-linked hyper IgM syndrome complicated with toxoplasmic encephalitis in a child: A case report and literature review.

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BACKGROUND The X-linked hyper-immunoglobulin M syndrome (XHIGM) is an uncommon primary combined immunodeficiency disease caused by CD40L gene mutations. A delayed or missed diagnosis of XHIGM is common and concerning, owing to atypical immunoglobulin profile and phenotype of some patients, low

Onychomadesis in a patient with immunoglobulin class switch recombination deficiency.

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Immunoglobulin class switch recombination deficiencies (Ig CSR deficiencies) or Hyper IgM syndromes (HIGM) are a group of primary immunodeficiency diseases, characterized by defective CD40 signaling of B cells, resulting in reduced CSR and somatic hypermutation. The affected patients are

Clinical features and genetic analysis of 20 Chinese patients with X-linked hyper-IgM syndrome.

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X-linked hyper-IgM syndrome (XHIGM) is one type of primary immunodeficiency diseases, resulting from defects in the CD40 ligand/CD40 signaling pathways. We retrospectively analyzed the clinical and molecular features of 20 Chinese patients diagnosed and followed up in hospitals affiliated to

Gastrointestinal cytomegalovirus disease in a patient with pemphigus vulgaris treated with corticosteroid and mycophenolate mofetil.

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Pemphigus vulgaris is an autoimmune disease characterized by the formation of suprabasal intra-epidermal blisters on the skin and mucosal surfaces. Infectious diseases are the main cause of death in patients with pemphigus due to the disrupture of the physiological skin barrier, immune

Behçet's disease in childhood: report of one case.

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We report on a 6 yr 7 m-old girl who had suffered from recurrent oral ulcers since July, 2000. Anal ulcers were also noted initially, and arthralgia was observed. Skin testing (pathergy test) showed only mild erythematous changes over the test area. HLA typing revealed HLA-B56. Intestinal symptoms

Neutropenia in patients with primary antibody deficiency disorders.

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Neutropenia is characterized by decrease in the absolute number of circulating neutrophils and an increase susceptibility to infections. The current study was performed in order to explain the clinical and laboratory findings of patients with antibody deficiency disorders associated neutropenia. The

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