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6 výsledky
Integrating Transcriptome and Experiments Reveals the Anti-diabetic Mechanism of Cyclocarya paliurus Formula.
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Type 2 diabetes (T2D) is generally regarded as a metabolic disorder disease with various phenotypic expressions. Traditional Chinese medicine (TCM) has been widely used for preventing and treating diabetes. In our study, we demonstrated that Cyclocarya paliurus formula extractum (CPE), a compound of
Sulfated polysaccharide from Cyclocarya paliurus enhances the immunomodulatory activity of macrophages.
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In this study, a sulfated polysaccharide (S-CP1-8) was obtained from Cyclocarya paliurus by chlorosulfonic acid-pyridine method. S-CP1-8 was chemical characterized and cultured with macrophage RAW264.7 cells to evaluate its immunomodulatory activity. Preliminary physicochemical analysis identified
3,4-Seco-Dammarane Triterpenoid Saponins with Anti-inflammatory Activity Isolated from the Leaves of Cyclocarya paliurus.
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Cyclocarya paliurus is commonly used for the prevention and treatment of hypertension, diabetes, and inflammation in South China. Although research on the anti-inflammatory effects of C. paliurus leaves has been reported, no active anti-inflammatory compounds have been identified. In the present
Cyclocarya paliurus Triterpenoids Improve Diabetes-Induced Hepatic Inflammation via the Rho-Kinase-Dependent Pathway.
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This study aimed to assess the effects of triterpene extract of Cyclocarya paliurus (Batal.) Iljinskaja (CPT) on diabetes-induced hepatic inflammation and to unveil the underlying mechanisms. Diabetes in db/db mice was alleviated after CPT administration, as assessed by the oral glucose
Antihyperlipidaemic effect of triterpenic acid-enriched fraction from Cyclocarya paliurus leaves in hyperlipidaemic rats.
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BACKGROUND
Cyclocarya paliurus (Batal) Iljinskaja (Juglandaceae) is an edible and medicinal plant; the leaves are used in Chinese folkloric medicine to treat dyslipidaemia and diabetes.
OBJECTIVE
This study evaluates the antihyperlipidaemic potential of the triterpenic acid-enriched fraction (TAE)
Antihyperlipidemic effect of Cyclocarya paliurus (Batal.) Iljinskaja extract and inhibition of apolipoprotein B48 overproduction in hyperlipidemic mice.
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BACKGROUND
Cyclocarya paliurus (CP) Batal., the sole species in its genus, is a native plant to China. As a traditional Chinese folk medicine, the tree leaves have been widely used for the treatment of metabolic disorders, including hyperlipidemia, obesity, diabetes and hypertension.
OBJECTIVE
The
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