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thymine/zhubný nádor
Odkaz sa uloží do schránky
Strana 1 od 16 výsledky
Combination of DNA repair inhibition with bendamustine or gemcitabine in the treatment of cancer
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REFERENCE TO A SEQUENCE LISTING
This application includes a Sequence Listing submitted electronically as a text file named TDG_ST25.txt, created on Mar. 12, 2013 with a size of 1,000 bytes. The Sequence Listing is incorporated by reference herein.
FIELD OF THE INVENTION
The invention relates
Combination of DNA repair inhibition with bendamustine or gemcitabine in the treatment of cancer
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REFERENCE TO A SEQUENCE LISTING
This application includes a Sequence Listing submitted electronically as a text file named TDG_ST25.txt, created on Mar. 12, 2013 with a size of 1,000 bytes. The Sequence Listing is incorporated by reference herein.
FIELD OF THE INVENTION
The invention relates
Pharmaceutical composition for the treatment of malignant neoplasms and immunosuppressive deficiencies and its method of production
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FIELD OF THE INVENTION
The present invention refers to a pharmaceutical composition for the treatment of malignant neoplasms and immunosuppressive deficiencies, by re-establishing the biochemical balance within the cells, mainly those cells undergoing a disordered reproduction, and to a method for
BRAF mutation T1796A in thyroid cancers
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FIELD OF THE INVENTION
The invention relates to diagnostic, therapeutic, and prognostic methods for thyroid cancers.
BACKGROUND OF THE INVENTION
Raf kinase is a key component of the RAS.fwdarw.Raf.fwdarw.MEK.fwdarw.ERK/MAP kinase signaling pathway, which plays a fundamental role in the regulation of
BRAF mutation T1796A in thyroid cancers
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FIELD OF THE INVENTION
The invention relates to diagnostic, therapeutic, and prognostic methods for thyroid cancers.
BACKGROUND OF THE INVENTION
Raf kinase is a key component of the RAS.fwdarw.Raf.fwdarw.MEK.fwdarw.ERK/MAP kinase signaling pathway, which plays a fundamental role in the regulation of
Diagnostic assay for cancer susceptibility
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TECHNICAL FIELD OF THE INVENTION
The invention relates to a diagnostic assay for determining susceptibility to cancer based on the sequence of the 3' untranslated region of the prohibitin gene.
BACKGROUND OF THE INVENTION
While the success of cancer treatment depends greatly on early detection, many
Diagnostic assay for breast cancer susceptibility
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TECHNICAL FIELD OF THE INVENTION
The invention relates to a diagnostic assay for determining susceptibility to breast cancer based on the sequence of the 3' untranslated region of the prohibitin gene.
BACKGROUND OF THE INVENTION
Breast cancer is the second leading cause of cancer-related deaths of
Pharmaceutical composition for treating and/or preventing cancer
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TECHNICAL FIELD
The present invention relates to a pharmaceutical composition for treating and/or preventing a cancer comprising, as an active ingredient, a polynucleotide derived from microRNA.
BACKGROUND ART
MicroRNA (miRNA) is an RNA of 16 to 28 nucleotides that is not translated into a protein,
Method for detecting methylation status by using methylation-independent primers
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All patent and non-patent references cited in the application, or in the present application, are also hereby incorporated by reference in their entirety.
FIELD OF INVENTION
The present invention relates to a method of detecting methylated CpG-containing nucleic acids by nucleic acid amplification
Oligonucleotide compositions and their use to induce apoptosis
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FIELD OF THE INVENTION
The present invention relates to novel oligonucleotide compositions and methods of using them for alteration of cellular function including the inhibition of cellular proliferation, induction of cell cycle arrest and induction of apoptosis.
BACKGROUND OF THE
Oligonucleotide compositions and their use to induce apoptosis
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FIELD OF THE INVENTION
The present invention relates to novel oligonucleotide compositions and methods of using them for alteration of cellular function including the inhibition of cellular proliferation, induction of cell cycle arrest and induction of apoptosis.
BACKGROUND OF THE
Oligonucleotide compositions and their use to induce apoptosis
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FIELD OF THE INVENTION
The present invention relates to novel oligonucleotide compositions and methods of using them for alteration of cellular function including the inhibition of cellular proliferation, induction of cell cycle arrest and induction of apoptosis.
BACKGROUND OF THE
L-pyranosyl nucleosides
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FIELD OF THE INVENTION
This invention relates to L-pyranosyl nucleosides, processes for their preparation, pharmaceutical compositions containing such and methods of using such compounds as anticancer, antiviral, antifungal, antiparasitic and/or antibacterial agents in mammals.
BACKGROUND OF THE
L-erythrosyl nucleosides
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FIELD OF THE INVENTION
This invention relates to L-erythrosyl nucleosides, processes for their preparation, pharmaceutical compositions containing such and methods of using such compounds as anticancer, antiviral, antifungal, antiparasitic and/or antibacterial agents in meals.
BACKGROUND OF THE
Macroheterocyclic nucleoside derivatives and their analogues, production and use thereof
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FIELD OF INVENTION
The present invention relates to macroheterocyclic nucleoside derivatives and their analogues, production and use thereof. These compounds are the prodrugs for treating viral and cancerous diseases and are inhibitors of HCV NSSB polymerase, HBV DNA polimerase and HIV-1 reverse
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