uridine/únava organizmu

Odkaz sa uloží do schránky

Vyberte typ zoradenia

15 výsledky

Uridine diphosphate glucuronosyl transferase 1A1 promoter polymorphism predicts the risk of gastrointestinal toxicity and fatigue induced by irinotecan-based chemotherapy.

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

BACKGROUND In the current Phase II study, the authors evaluated the association between genomic polymorphic variants in uridine diphosphate glucuronosyl transferase (UGT1A1), methylenetetrahydrofolate reductase (MTHFR), and thymidylate synthase (TS) genes, and the incidence of the adverse effects of

[Uridine triphosphate in a vitamin association in prevention of fatigue].

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

[Uridine-5-triphosphoric acid (UTP) in fatigue-induced electromyographic changes].

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

[Uridine-5-triphosphoric acid in therapeutics. II. Treatment of myopathies, myotonia, myasthenia and fatigue states].

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

Early-Onset 5-Fluorouracil Toxicity in a Patient Negative for Dihydropyrimidine Dehydrogenase Mutations: The Clinical Course of Reversal with Uridine Triacetate.

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

An antimetabolite pyridine analog, 5-fluorouracil (5-FU), is used to treat solid tumors. Early toxicities may occur at standard doses of 5-FU due to dihydropyrimidine dehydrogenase (DPD) deficiency. Uridine triacetate, approved by the Food and Drug Administration in 2015, is an oral prodrug of

Phase I clinical and pharmacological studies of benzylacyclouridine, a uridine phosphorylase inhibitor.

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

Benzylacyclouridine (BAU, IND 039655) is a potent and specific inhibitor of uridine phosphorylase (UrdPase; EC 2.4.2.3). This enzyme plays a major role in regulating uridine homeostasis and also catalyzes the conversion of fluoropyrimidine nucleosides to their respective bases. Inhibition of UrdPase

Effect of the nucleotides CMP and UMP on exhaustion in exercise rats.

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

The aetiology of muscle fatigue has yet not been clearly established. Administration of two nucleotides, cytosine monophosphate (CMP) and uridine monophosphate (UMP), has been prescribed for the treatment of neuromuscular affections in humans. Patients treated with CMP/UMP recover from altered

Rapid activation of glycogen synthase and protein phosphatase in human skeletal muscle after isometric contraction requires an intact circulation.

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

The effects of isometric contraction (66% of maximal force) and recovery on glycogen synthase fractional activity (GSF) in human skeletal muscle have been studied. Biopsies were taken from the quadriceps femoris muscle at rest, at fatigue and 5 min postexercise on two occasions: after one of the

[Microbial synthesis of salidroside].

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

Salidroside, as one of the main active ingredients of Rhodiala plant, has the effects of anti-hypoxia, anti-radiation, anti-fatigue, anti-tumor, hypoglycemia and improving immunity. With the increasing demand for salidroside and the decreasing of plant resources, microbial production of salidroside

Changing the face of hepatitis C management - the design and development of sofosbuvir.

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

The availability of direct-acting antiviral (DAA) therapy has launched a new era in the management of chronic hepatitis C. Sofosbuvir, a uridine nucleotide analog that inhibits the hepatitis C RNA-dependent RNA polymerase, is the backbone of chronic hepatitis C therapy. Acting at the catalytic site

Sorafenib: a review of its use in advanced hepatocellular carcinoma.

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

Sorafenib (Nexavar) is an orally active multikinase inhibitor that is approved in the EU for the treatment of hepatocellular carcinoma. Monotherapy with sorafenib prolongs overall survival and delays the time to progression in patients with advanced hepatocellular carcinoma who are not candidates

Sofosbuvir in combination with peginterferon alfa-2a and ribavirin for non-cirrhotic, treatment-naive patients with genotypes 1, 2, and 3 hepatitis C infection: a randomised, double-blind, phase 2 trial.

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

BACKGROUND Protease inhibitors have improved treatment of infection with hepatitis C virus (HCV), but dosing, a low barrier to resistance, drug interactions, and side-effects restrict their use. We assessed the safety and efficacy of sofosbuvir, a uridine nucleotide analogue, in treatment-naive

Metabolic profiles of exercise in patients with McArdle disease or mitochondrial myopathy.

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

McArdle disease and mitochondrial myopathy impair muscle oxidative phosphorylation (OXPHOS) by distinct mechanisms: the former by restricting oxidative substrate availability caused by blocked glycogen breakdown, the latter because of intrinsic respiratory chain defects. We applied metabolic

Vorinostat: A novel therapy for the treatment of cutaneous T-cell lymphoma.

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

OBJECTIVE The pharmacology, pharmacokinetics, clinical efficacy, safety, adverse effects, dosage and administration, and role in therapy of vorinostat in the treatment of cutaneous T-cell lymphoma (CTCL) are reviewed. CONCLUSIONS Vorinostat is a novel histone deacetylase (HDAC) inhibitor approved

Mutation in human selenocysteine transfer RNA selectively disrupts selenoprotein synthesis.

Články môžu prekladať iba registrovaní používatelia

Prihlásiť Registrácia

Selenium is a trace element that is essential for human health and is incorporated into more than 25 human selenocysteine-containing (Sec-containing) proteins via unique Sec-insertion machinery that includes a specific, nuclear genome-encoded, transfer RNA (tRNA[Ser]Sec). Here, we have identified a

Pripojte sa k našej
facebookovej stránke

Herbal & Natural Medicine

Najkompletnejšia databáza liečivých bylín podporovaná vedou

Pracuje v 55 jazykoch
Bylinné lieky podporené vedou
Rozpoznávanie bylín podľa obrázka
Interaktívna GPS mapa - označte byliny na mieste (už čoskoro)
Prečítajte si vedecké publikácie týkajúce sa vášho hľadania
Vyhľadajte liečivé byliny podľa ich účinkov
Usporiadajte svoje záujmy a držte krok s novinkami, klinickými skúškami a patentmi

Zadajte príznak alebo chorobu a prečítajte si o bylinách, ktoré by vám mohli pomôcť, napíšte bylinu a pozrite sa na choroby a príznaky, proti ktorým sa používa.
* Všetky informácie sú založené na publikovanom vedeckom výskume