Nature clinical practice. Nephrology 2009-Mar
A case of tuberous sclerosis complex that progressed to end-stage renal disease.
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BACKGROUND
A 31-year-old woman with tuberous sclerosis complex presented with a 1 week history of subjective fever, chills, rigors, poor appetite and dizziness.
METHODS
Physical examination, urine and blood analysis, CT of the abdomen, chest and brain, and chest X-ray.
METHODS
End-stage renal disease, septic shock and urinary tract infection secondary to huge bilateral angiomyolipomas of the kidney associated with tuberous sclerosis complex.
RESULTS
Antibiotic therapy, vasopressor treatment and bilateral nephrectomy, followed by hemodialysis while awaiting renal transplantation.
