3 o beta d glucopyranoside/levkemija

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Two flavonoids from the leaves of Morus alba induce differentiation of the human promyelocytic leukemia (HL-60) cell line.

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Prijava / prijava

Two flavonoids, quercetin-3-O-beta-D-glucopyranoside (1) and quercetin-3,7-di-O-beta-D-glucopyranoside (2), were isolated from the leaves of Morus alba (Moraceae). These two flavonoids exerted a significant inhibitory effect on the growth of the human promyelocytic leukemia cell line (HL-60) at the

A new drimane sesquiterpenoid glycoside from the seeds of Antiaris toxicaria.

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Prijava / prijava

A new drimane sesquiterpenoid glycoside, named 7-drimen-3β,11-diol 3-O-β-d-glucopyranoside, was isolated from the 95% EtOH extract of the seeds of Antiaris toxicaria (Pers.) Lesch. The chemical structure was completely elucidated using a combination of 1D and 2D NMR techniques (COSY, HMQC, HMBC, and

New benzoyl glucosides and cytotoxic pterosin sesquiterpenes from Pteris ensiformis Burm.

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Three new compounds: 2R,3R-pterosin L 3-O-beta-D-glucopyranoside (1), beta-D-xylopyranosyl(1-->2)-7-O-benzoyl-beta-D-glucopyranoside (2) and 4-O-benzoyl-beta-D-xylo-pyranosyl(1-->2)-7-O-benzoyl-beta-D-glucopyranoside (3), together with nine known compounds, were isolated from the ethyl acetate

Phytochemicals from Kaempferia angustifolia Rosc. and their cytotoxic and antimicrobial activities.

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Phytochemical investigation on rhizomes of Kaempferia angustifolia has afforded a new abietene diterpene, kaempfolienol (1) along with crotepoxide (2), boesenboxide (3), 2'-hydroxy-4,4',6'-trimethoxychalcone (4), zeylenol (5), 6-methylzeylenol (6), (24S)-24-methyl-5α-lanosta-9(11), 25-dien-3β-ol

Structural identification of methyl protodioscin metabolites in rats' urine and their antiproliferative activities against human tumor cell lines.

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Prijava / prijava

Methyl protodioscin (MPD), a furostanol saponin, is a preclinical drug shown potent antiproliferative activities against most cell lines from leukemia and solid tumors. The metabolites of MPD in rats' urine after single oral doses of 80 mg/kg were investigated in this research. Ten metabolites were

Isolation and identification of cytotoxic compounds from the rhizomes of Paris quadrifolia L.

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BACKGROUND Paris quadrifolia L. is a medicinal plant which contains steroidal saponins. The present study reports isolation and structural identification of six pennogenyl saponins obtained from P. quadrifolia rhizomes. The four spirostan saponins were obtained from P. quadrifolia for the first

Silvestrol and episilvestrol, potential anticancer rocaglate derivatives from Aglaia silvestris.

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Two cytotoxic rocaglate derivatives possessing an unusual dioxanyloxy unit, silvestrol (1) and episilvestrol (2), were isolated from the fruits and twigs of Aglaia silvestris by bioassay-guided fractionation monitored with a human oral epidermoid carcinoma (KB) cell line. Additionally, two new

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