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6 rezultatov
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Ovarian cancer (OVCA) is the deadliest type of malignant gynecological disease, and previous studies have demonstrated that estrogen receptor β (ERβ) serves important roles in this disease. Aconitine, a toxin produced by the Aconitum plant, displays potent effects against cancers. The aim of the
[Changes in the fatty acid composition of the phospholipids in the internal organs of rats during the modelling of aconitine arrhythmia].
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The changes of phospholipid fatty acid composition of the viscera were investigated in a model of aconitinic arrhythmia in rats by the GC method. Aconitinic arrhythmia leads to a reduction in a proportion of polyenic fatty acids (arachidonic, docosahexaenoic) and to an increase in that of saturated
The action of AD6 on experimental arrhythmias and on action potentials of cardiac fibers.
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Prijava / prijava
AD6 is a coumarinic derivative which increases both coronary blood flow and prostacyclin production, while it decreases platelet responsiveness. We tested its action on experimental cardiac arrhythmias. AD6 (2.5-10 mg/kg) was able to antagonize the arrhythmogenic action of aconitine in rats and of
Influence of arrhythmogenic and antiarrhythmic agents on alternating current-induced arrhythmias in guinea-pig heart preparations.
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Prijava / prijava
The method for inducing arrhythmias or asystole by the application of a 50 Hz alternating current (ac) has been applied to isolated guinea-pig left atria and papillary muscles in order to characterize arrhythmogenic and antiarrhythmic substances. Aconitine, BaCl2 (less than 2 mmol/l) and hypoxia
The roles of traditional chinese medicine: shen-fu injection on the postresuscitation care bundle.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Survival rates following in-hospital and out-of-hospital cardiac arrests remain disappointingly low. Organ injury caused by ischemia and hypoxia during prolonged cardiac arrest is compounded by reperfusion injury that occurs when a spontaneous circulation is restored. A bundle of procedures, which
Activation of histamine H3 receptors inhibits carrier-mediated norepinephrine release in a human model of protracted myocardial ischemia.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
During protracted myocardial ischemia, ATP depletion promotes Na+ accumulation in sympathetic terminals and prevents vesicular storage of norepinephrine (NE). This forces the reversal of the neuronal uptake1 transporter, and NE is massively released (carrier-mediated release). We had shown that
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