andrographis/carbohydrate

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Carbohydrate Modifications of Neoandrographolide for Improved Reactive Oxygen Species-Mediated Apoptosis through Mitochondrial Pathway in Colon Cancer.

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Prijava / prijava

Modifications at the carbohydrate moiety of neoandrographolide, isolated from the medicinal plant Andrographis paniculata, result in more potent and less toxic derivatives, namely, 4',6'-benzylidene neoandrographolide (2b) and 4'6'-p-methoxybenzylidene neoandrographolide

Inhibition of galectin-3 mediated cellular interactions by pectic polysaccharides from dietary sources.

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Prijava / prijava

Pectic polysaccharides from dietary sources such as Decalepis hamiltonii--swallow root (SRPP), Hemidesmus indicus (HPP), Nigella sativa--black cumin (BCPP), Andrographis serpyllifolia-(APP), Zingiber officinale--ginger (GRPP) and, citrus pectin (CPP) were examined for galectin inhibitory activity.

Characterisation and immuno-stimulating activity of polysaccharides from Thai medicinal plants.

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Prijava / prijava

Water-soluble polysaccharides were isolated from the tubers of Butea superba Roxb. and Pueraria candollei Wall. Ex Benth. var. mirifica (Shaw et Suvat.) C. Niyomdham, the leaves of Centella asiatica (L.) Urb, Ocimum basilicum L., Psidium guajava and Andrographis paniculata (Burn. f.) Nees, the stems

Andrographolide and kalmegh (Andrographis paniculata) extract: effect on intestinal brush-border membrane-bound hydrolases.

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Prijava / prijava

Oral (p.o.) administration of a single dose of kalmegh leaf extract (KE; 0.5 g/kg and 1.0 g/kg) or andrographolide (A; 5 mg/kg and 10 mg/kg) to adult male albino rats (100-120 g) produced a dose-related and time-dependent characteristic activation of brush-border membrane-bound hydrolases, viz.

Andrographis paniculata transcriptome provides molecular insights into tissue-specific accumulation of medicinal diterpenes.

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Prijava / prijava

BACKGROUND Kalmegh (Andrographis paniculata) has been widely exploited in traditional medicine for the treatment of infectious diseases and health disorders. Ent-labdane-related diterpene (ent-LRD) specialized (i.e., secondary) metabolites of kalmegh such as andrographolide, neoandrographolide and

Discovery of an interplay between the gut microbiota and esophageal squamous cell carcinoma in mice

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Prijava / prijava

Esophageal squamous cell carcinoma (ESCC) is the main type of esophageal cancer (EC) worldwide, causing half a million deaths each year. Recent evidence has demonstrated the role of the gut microbiota in health and disease. However, our current understanding of the gut microbiome in EC remains

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