antiasthmatic/bruhanje

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The anti-asthmatic drug pranlukast suppresses the delayed-phase vomiting and reverses intracellular indices of emesis evoked by cisplatin in the least shrew (Cryptotis parva).

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Prijava / prijava

The introduction of second generation serotonin 5-HT3 receptor (5-HT3) antagonist palonosetron combined with long-acting substance P neurokinin NK1 receptor (NK1) antagonists (e.g. netupitant) has substantially improved antiemetic therapy against early- and delayed-phases of emesis caused by highly

Intravenous administration of enprofylline to asthmatic patients.

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Prijava / prijava

In 6 asthmatic patients, the possibility of obtaining a steady state plasma level of 5 mg/l of enprofylline by administration of two constant rate infusions was examined. The simulated plasma concentration curves, based on information from preassessment of individual pharmacokinetic parameters, were

Discovery of a novel orally active PDE-4 inhibitor effective in an ovalbumin-induced asthma murine model.

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Prijava / prijava

Phosphodiesterase-4 (PDE-4) is responsible for metabolizing adenosine 3',5'-cyclic monophosphate that reduces the activation of a wide range of inflammatory cells including eosinophils. PDE-4 inhibitors are under development for the treatment of respiratory diseases such as asthma and chronic

A review of the ethnopharmacology, phytochemistry, and pharmacology of Changium smyrnioides Wolff.

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Prijava / prijava

Changium smyrnioides Wolff is a monotypic species of the genus Changium Wolff which is only found in eastern China. C. smyrnioides has been used as a traditional medicine for ages to treat cough, vomiting, nausea, megrim, and carbuncle. It is also widely used to brew medicated liquor and health tea

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