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atherosclerosis/tyrosine
Povezava se shrani v odložišče
Stran 1 iz 70 rezultatov
Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The present invention relates to a series of substituted heteroaromatic compounds, methods for their preparation, pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to bioisosteres of quinoline and quinazoline derivatives which exhibit protein
N-[4-(3-chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazoli n-6-yl]-acrylamide, and irreversible inhibitor of tyrosine kinases
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
FIELD OF THE INVENTION
This invention relates to the compound N-[4-(3-chloro-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazol in-6-yl]-acrylamide that is an irreversible inhibitor of tyrosine kinases. This invention also relates to a method of treating cancer, atherosclerosis, restenosis,
Tyrosine kinase inhibitors
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND OF THE INVENTION
Tyrosine kinases are a class of enzymes that catalyze the transfer of the terminal phosphate of adenosine triphospate to tyrosine residues in protein substrates. Tyrosine kinases are believed, by way of substrate phosphorylation, to play critical roles in signal
Dihydroxyindanone tyrosine kinase inhibitors
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
This invention relates to dihydroxyindanone compounds which are tyrosine kinase inhibitors useful for the control of cancer, antiangiogenesis and atherosclerosis.
BACKGROUND OF THE INVENTION
Tyrosine-specific protein kinases (tyrosine kinases) represent a family of enzymes which catalyze the
Tyrosine kinase inhibitors
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND OF THE INVENTION
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,
Tyrosine kinase inhibitors
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND OF THE INVENTION
The present invention relates to imidazopyridine compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such
Tyrosine kinase inhibitors
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND OF THE INVENTION
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,
Tyrosine kinase inhibitors
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND OF THE INVENTION
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,
Tyrosine kinase inhibitors
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND OF THE INVENTION
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,
Tyrosine kinase inhibitors
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND OF THE INVENTION
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,
Tyrosine kinase inhibitors
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND OF THE INVENTION
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,
Tyrosine kinase inhibitors
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND OF THE INVENTION
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,
Tyrosine kinase inhibitors
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND OF THE INVENTION
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,
Tyrosine kinase inhibitors
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND OF THE INVENTION
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,
Tyrosine kinase inhibitors
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND OF THE INVENTION
The present invention relates to compounds which inhibit, regulate and/or modulate tyrosine kinase signal transduction, compositions which contain these compounds, and methods of using them to treat tyrosine kinase-dependent diseases and conditions, such as angiogenesis,
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