catechol/vnetje

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Catechol carboxylic acids

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Prijava / prijava

BRIEF DESCRIPTION OF THE INVENTION The invention relates to catechol carboxylic acid derivatives of the formula ##STR7## wherein R.sub.1 is ##STR8## hydrogen, acetyl, hydroxy or alkanoyloxy, R.sub.2 is ##STR9## hydroxy, hydrogen or alkanoyloxy, wherein R is hydrogen, lower alkyl or

Catechol carboxylic acids

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Prijava / prijava

Catechol diethers as selective PDE.sup.IV inhibitors

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Prijava / prijava

BACKGROUND OF THE INVENTION This invention relates to a series of 4-substituted catechol diether compounds which are selective inhibitors of phosphodiesterase (PDE) type IV and as such are useful in the treatment of AIDS, asthma, arthritis, bronchitis, chronic obstructive airways disease, psoriasis,

Therapeutically active compounds based on indazole bioisostere replacement of catechol in PDE4 inhibitors

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Prijava / prijava

FIELD OF THE INVENTION The present invention is in the field of compositions of matter, and pharmaceutical compositions and methods of treatment utilizing one or more of said compositions of matter as the active ingredient and the active agent with respect thereto, wherein said composition of matter

Catechol derivatives and pharmaceutical compositions thereof for inhibiting anaphylaxis (SRS-A)

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Prijava / prijava

FIELD OF THE INVENTION This invention relates to novel catechol derivatives useful for medicaments and intermediates thereof. BACKGROUND OF THE INVENTION It is generally considered that in allergic asthma and other atopic diseases of man or anaphylactic shock in animals, several chemical mediators

Catechol diether compounds as inhibitors of TNF release

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Prijava / prijava

BACKGROUND OF THE INVENTION This invention relates to a method of inhibiting production of TNF (tumor necrosis factor) in a mammal in need thereof which method comprises administering to said mammal an effective amount of a compound of the formula (I) (shown below) or a pharmaceutically acceptable

4-(or 5-) substituted catechol derivatives

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Prijava / prijava

FIELD OF THE INVENTION The invention relates to 4-substituted or 5-substituted catechol derivatives that are useful for treating stroke, myocardial infarct, and cardiovascular inflammatory conditions, to pharmaceutical compositions comprising these compounds, and to methods for the treatment of

Catechol diethers derivatives useful as pharmaceutical agents

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Prijava / prijava

BACKGROUND OF THE INVENTION This invention relates to catechol diethers containing a long lipophilic sidechain which are selective inhibitors of phosphodiesterase (PDE) type IV or the production of tumor necrosis factor (TNF) and as such are useful in the treatment of asthma, arthritis, bronchitis,

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Herbal & Natural Medicine

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