5 rezultatov
BACKGROUND OF THE INVENTION
The prevalence of asthma has been steadily increasing for the past two decades, with an estimated 17 million cases in the United States alone. Once believed to be primarily a dysfunction in the contractile mechanisms of airway smooth muscles, recent studies have indicated
REFERENCE TO SEQUENCE LISTING
The Sequence Listing submitted in the ASCII text file named 047162-5052-05-US.455194_Sequence_Listing.txt is hereby incorporated by reference. The file size is 5 kb and the date of creation is Feb. 1, 2013.
BACKGROUND OF THE INVENTION
The prevalence of asthma has been
BACKGROUND OF THE INVENTION
Acidic mammalian chitinase (AMCase; M.sub.r=.about.52.2 kD) is a secreted enzyme, typically found in the stomach, salivary gland, and lungs. Unique among mammalian enzymes in that it has an acidic pH optimum, the enzyme catalyzes the hydrolysis of artificial chitin-like
BACKGROUND OF THE INVENTION
Acidic mammalian chitinase (AMCase; M.sub.r=.about.52.2 kD) is a secreted enzyme, typically found in the stomach, salivary gland, and lungs. Unique among mammalian enzymes in that it has an acidic pH optimum, the enzyme catalyzes the hydrolysis of artificial chitin-like
BACKGROUND OF THE INVENTION
Acidic mammalian chitinase (AMCase; M.sub.r=.about.52.2 kD) is a secreted enzyme, typically found in the stomach, salivary gland, and lungs. Unique among mammalian enzymes in that it has an acidic pH optimum, the enzyme catalyzes the hydrolysis of artificial chitin-like