flavonol glycoside/rak dojke

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Antioxidative, Anti-Inflammatory, and Anticancer Effects of Purified Flavonol Glycosides and Aglycones in Green Tea.

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Prijava / prijava

(1) Background: Extensive research has focused on flavan-3-ols, but information about the bioactivities of green tea flavonols is limited. (2) Methods: In this study, we investigated the antioxidative, anti-inflammatory, and anticancer effects of flavonol glycosides and aglycones from green tea

Induction of apoptosis by Icariside II through extrinsic and intrinsic signaling pathways in human breast cancer MCF7 cells.

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Prijava / prijava

The anti-tumor effect of Icariside II (IcaS), a natural prenylated flavonol glycoside, was studied on human breast cancer MCF7 cells to unveil the underlying mechanisms involved. IcaS in MCF7 cells produced a loss of mitochondrial membrane potential and release of cytochrome c and apoptosis-inducing

Rutin as A Novel c-Met Inhibitory Lead for The Control of Triple Negative Breast Malignancies.

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Prijava / prijava

Triple negative breast cancer (TNBC) has high metastatic and mortality potential and lacks effective and selective therapeutic options. Aberrant dysregulation of the receptor tyrosine kinase c-Met promotes TNBC progression, motility and survival and therefore considered a valid therapeutic target.

Icariin-induced inhibition of SIRT6/NF-κB triggers redox mediated apoptosis and enhances anti-tumor immunity in TNBC

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Prijava / prijava

Abnormal activation of Nuclear factor kappa B (NF-κB) signaling pathway is closely implicated in triple-negative breast cancer (TNBC) growth, metastasis and tumor immune escape. In this study, the anti-cancer effects of icariin, a natural flavonol glycoside, towards breast cancer cells and the

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