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glucuronic acid/rak dojke
Povezava se shrani v odložišče
Stran 1 iz 36 rezultatov
[Glucuronic acid, glucuronyltransferase and estrogens in breast cancer and precancer].
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The glucuronic acid level in the serum and urine, the diural excretion of estrogens and 17-KS with the urine, the activity of glucuronyltransferase are reported in 101 patients with benign and malignant tumors and in 22 healthy females. The decrease in the activity of glucurolytransferase and
[Serum and urine glucuronic acid in breast cancer and precancer].
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
[The diagnostic significance of urinary glucuronic acid levels in breast cancer patients].
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
[Free and glucuronic acid-bound 17-hydroxycorticosteroids in the plasma of patients with breast cancer during intravenous infusion of ACTH].
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Biochemical evaluation of hyaluronic acid in breast cancer.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
The latest experimental studies on human cancer diseases have observed the bioactive role of hyaluronic acid (HA) during carcinogenesis. HA is a component of the extra-cellular matrix (ECM). It is closely correlated with tumor cell growth, proliferation, and metastasis. The present study
Estrogen regulation of the glucuronidation enzyme UGT2B15 in estrogen receptor-positive breast cancer cells.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Estrogens and androgens influence many properties of breast cancer cells; hence, regulation of local estrogen and androgen levels by enzymes involved in steroid hormone biosynthesis and metabolism would impact signaling by these hormones in breast cancer cells. In this study, we show that the
Inhibition of human UDP-glucose dehydrogenase expression using siRNA expression vector in breast cancer cells.
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Prijava / prijava
UDP-glucose dehydrogenase (UGDH) catalyzes two oxidations of UDP-glucose to yield UDP-glucuronic acid. Pathological over-production of extracellular matrix components may be linked to the availability of UDP-glucuronic acid, therefore UGDH is a potential therapeutic target. RNA interference (RNAi)
A glucuronic acid binding leguminous lectin with mitogenic activity toward mouse splenocytes.
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Prijava / prijava
A dimeric 64-kDa lectin was purified from seeds of French bean (Phaseolus vulgaris) cultivar number 1. The purification protocol entailed Q-Sepharose, Affi-gel blue gel, Mono S and Superdex 75. The lectin-enriched fraction was adsorbed on Q-Sepharose and Affi-gel blue gel and desorbed using 1M NaCl
Intestinal breast cancer resistance protein (BCRP)/Bcrp1 and multidrug resistance protein 3 (MRP3)/Mrp3 are involved in the pharmacokinetics of resveratrol.
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Prijava / prijava
The phytoestrogen resveratrol has putative health-promoting effects and is present in several dietary constituents. Resveratrol is metabolized extensively in the gut epithelium, resulting in the formation of hydrophilic glucuronic acid and sulfate conjugates. These polar resveratrol conjugates need
Characterization of a polysaccharide from Sanghuangporus vaninii and its antitumor regulation via activation of the p53 signaling pathway in breast cancer MCF-7 cells
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Prijava / prijava
Sanghuangporus is a traditional medicine that has been used for nearly 2000 years in Asia. It has been found to enhance immunity and have anticancer properties. Some studies determined that Sanghuangporus polysaccharide can inhibit tumors in vitro, although the underlying mechanisms remain unknown.
Dermatan sulfate epimerase 1 expression and mislocalization may interfere with dermatan sulfate synthesis and breast cancer cell growth.
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Prijava / prijava
Dermatan sulfate (DS) is a glycosaminoglycan (GAG) that is produced through the epimerization of the glucuronic acid on chondroitin sulfate into iduronic acid (IduA) by dermatan sulfate epimerase (DS-epi) 1 and 2. Proteoglycans (PGs) play essential physiological and pathological roles during
Preparation, Characterization, and Inhibition of Hyaluronic Acid Oligosaccharides in Triple-Negative Breast Cancer.
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Prijava / prijava
Hyaluronic acid (hyaluronan, HA) is a critical component of the extracellular matrix and plays an important biological function of interacting with different molecules and receptors. In this study, both odd- and even-numbered HA oligosaccharides (HAOs) with specific degrees of polymerization (DP)
Development of a novel metastatic breast cancer score based on hyaluronic acid metabolism.
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Prijava / prijava
Tumor metastasis involves the dissemination of malignant cells into the basement membrane, and the vascular system contributes to the circulating pool of these markers. In this context, our aim has been focused on the development of a non-invasive score based on degradation of the backbone of
UDP-sugar accumulation drives hyaluronan synthesis in breast cancer.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Increased uptake of glucose, a general hallmark of malignant tumors, leads to an accumulation of intermediate metabolites of glycolysis. We investigated whether the high supply of these intermediates promotes their flow into UDP-sugars, and consequently into hyaluronan, a tumor-promoting matrix
UDP-glucose 6-dehydrogenase regulates hyaluronic acid production and promotes breast cancer progression.
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Prijava / prijava
An improved understanding of the biochemical alterations that accompany tumor progression and metastasis is necessary to inform the next generation of diagnostic tools and targeted therapies. Metabolic reprogramming is known to occur during the epithelial-mesenchymal transition (EMT), a process that
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