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hemangiosarcoma/phosphatase
Povezava se shrani v odložišče
Stran 1 iz 26 rezultatov
Mutations of phosphatase and tensin homolog deleted from chromosome 10 in canine hemangiosarcoma.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
We examined the presence of phosphatase and tensin homolog deleted from chromosome 10 (PTEN) abnormalities that could contribute to the origin or progression of naturally occurring canine endothelial tumors (hemangiosarcoma). Our results document somatic point mutations or deletions encompassing the
Primary composite angiogenic leiomyosarcoma-epithelioid angiosarcoma of the brain.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The authors describe a primary sarcoma of the brain with immunohistochemical and ultrastructural features of leiomyosarcoma as well as epithelioid hemangiosarcoma. The leiomyosarcomatous component consisted of spindle cells with well-developed external lamina, subsarcolemmal densities composed of
Vascular sarcomas (probably angiosarcomas) transplanted from suspensions of liver cells from diethylnitrosamine-treated rats.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
F344 male rats were given 90 ppm diethylnitrosamine in their drinking water ad libitum in two cycles. Livers containing neoplastic nodules, hepatomas, and no sarcomas in the sections sampled were digested in parallel with 0.05% collagenase, 0.1% Pronase, or 0.25% trypsin. Cells were transplanted
Alterations of the p53 and PIK3CA/AKT/mTOR pathways in angiosarcomas: a pattern distinct from other sarcomas with complex genomics.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
The p53 and phosphoinositide-3-kinase, catalytic, alpha polypeptide/v-akt murine thymoma viral oncogene homolog/mechanistic target of rapamycin (PIK3CA/AKT/mTOR) pathways frequently are altered in sarcoma with complex genomics, such as leiomyosarcoma (LMS) or undifferentiated pleomorphic
Histogenesis of Kaposi's sarcoma and angiosarcoma of the face and the scalp.
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Prijava / prijava
This study reviews data on the histogenesis of Kaposi's sarcoma and angiosarcoma derived from clinical features, histology, electron microscopy, enzyme histochemistry, and immunochemistry of both diseases. Their hemorrhagic clinical appearance contrasts the predominantly lymphatic histologic
Epithelioid angiosarcoma: a neoplasm with potential diagnostic challenges.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Epithelioid angiosarcomas are extremely rare tumors associated with poor prognosis and early metastases. Its epithelioid cytomorphology and limited vasoformation make it difficult to distinguish from more common malignancies, such as, carcinoma. This can be a potential diagnostic pitfall for the
MULTICENTRIC T-CELL LYMPHOMA AND CUTANEOUS HEMANGIOSARCOMA IN A CAPTIVE CHEETAH (ACINONYX JUBATUS).
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
A 13-yr-old intact male cheetah (Acinonyx jubatus) presented for evaluation after a 4-mo history of intermittent lethargy and increased expiratory effort. The clinical signs were initially noted after the diagnosis and death of its 13-yr-old male sibling with solitary hepatic T-cell lymphoma.
Anastomosing hemangioma of the genitourinary tract: a lesion mimicking angiosarcoma.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
We describe 6 cases of a poorly recognized vascular neoplasm that can simulate angiosarcoma.
METHODS
Cases of a rare vascular tumor with a proclivity for the genitourinary tract encountered in our consultation material were prospectively collected between the year 1999 and 2008. Follow-up
Mutation of the PTEN gene in a human hepatic angiosarcoma.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The phosphatase and tensin homolog (mutated in multiple advanced cancers 1) gene, or PTEN, encodes a lipid phosphatase that contains a PTPase domain and a C2 domain and plays a role as a tumor suppressor that negatively regulates the cell-survival signaling pathway initiated by phosphatidylinositol
Intraneural angiosarcoma and angiosarcoma arising in benign and malignant peripheral nerve sheath tumours: clinicopathological and immunohistochemical analysis of four cases.
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Prijava / prijava
OBJECTIVE
Angiosarcomatous differentiation represents the least common form of heterologous differentiation in malignant peripheral nerve sheath tumours (MPNST), and is seen most frequently in patients with neurofibromatosis type 1. More rarely, it has been reported in patients without stigmata of
ROCK1 & 2 perform overlapping and unique roles in angiogenesis and angiosarcoma tumor progression.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The serine/threonine protein kinase paralogs ROCK1 & 2 have been implicated as essential modulators of angiogenesis; however their paralog-specific roles in endothelial function are unknown. shRNA knockdown of ROCK1 or 2 in endothelial cells resulted in a significant disruption of in vitro capillary
Splenic angiosarcoma presenting with jaundice, ascites and bone marrow fibrosis.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
A middle aged chronic alcoholic presented with deep jaundice, markedly enlarged and tender spleen with leukoerythroblastic blood picture and bone marrow biopsy showing mild fibrosis. He was tested negative for HIV, hepatitis B and C viruses. Besides very high serum bilirubin, alkaline phosphatase
Recurrent PTPRB and PLCG1 mutations in angiosarcoma.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Angiosarcoma is an aggressive malignancy that arises spontaneously or secondarily to ionizing radiation or chronic lymphoedema. Previous work has identified aberrant angiogenesis, including occasional somatic mutations in angiogenesis signaling genes, as a key driver of angiosarcoma. Here we
[Hemangiosarcoma of the liver. The diagnostic difficulties and therapeutic possibilities].
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Prijava / prijava
A 65-year-old man complained of decreasing physical capacity and weakness over the preceding six months, associated with marked painless jaundice and subsequently ascites. Despite extensive tests, some invasive, in three different hospitals no cause was found of the patient's symptoms and the marked
Methods for the differentiation of giant cells in canine and feline neoplasias in paraffin sections.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
In the following study cells with at least two cell nuclei are addressed as giant cells. In 47 biopsies of feline neoplasias (fibrosarcoma, haemangioendothelsarcoma, mammary adenocarcinoma, osteoidsarcoma, complex sarcoma), and 25 biopsies of canine neoplasias (malignant seminoma, mammary
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