hepatomegaly/albumin

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Prognostic significance of serum albumin in chronic lymphocytic leukemia.

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Prijava / prijava

BACKGROUND Low levels of serum albumin have been reported to be associated with a poor prognosis in lymphoproliferative disorders. RESULTS Clinical and laboratory data were retrospectively evaluated in a series of 342 patients with chronic lymphocytic leukemia (CLL). In univariate analysis, survival

Fulminant hepatic failure monitored by technetium-99m-DTPA-galactosyl-human serum albumin scintigraphy.

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Prijava / prijava

We describe a 43-yr-old woman with fulminant hepatic failure whose progress was monitored scintigraphically using 99m-Tc-galactosyl-human serum albumin (99mTc-GSA). On admission, the liver was atrophic and the heart was delineated distinctly by scintigraphy with 99m-Tc-GSA. The receptor index,

Evaluation of hepatic function with (99m)Tc-galactosylated serum albumin scintigraphy in patients with malaria: comparison with (99m)Tc-colloid scintigraphy and liver ultrasonography.

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Prijava / prijava

OBJECTIVE Malarial parasites injected by the mosquito rapidly target hepatocytes, and hepatomegaly is commonly observed during the progress of the disease in malaria patients. To evaluate the degree of hepatic damage and functional status of hepatocytes in malaria patients, we performed liver

Establishment of an albumin-deficient and fatty strain of rats.

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Prijava / prijava

An albumin-deficient and fatty strain of rats (AFR) was established from crosses between albumin-deficient rats (NAR) and fatty Zucker rats. AFRs have double homozygous mutant genes (alb/alb, fa/fa). The AFRs are heavier than the fatty Zucker rats and they have enlarged livers and adrenal glands. In

Hypoinsulinaemia has an important role in the development of oedema and hepatomegaly during malnutrition.

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Prijava / prijava

Various alterations in hormonal levels have been suggested to contribute to the development of nutritional oedema and fatty liver in children with kwashiorkor. We present an infant who underwent near-total pancreatectomy at the age of 4 weeks and developed kwashiorkor after 11 weeks. The sequence of

Alcoholic hepatomegaly: accumulation of protein in the liver.

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Prijava / prijava

The hepatomegaly that appears after long-term feeding of ethanol results in accumulation of protein that is quantitatively as important as the increase in lipid. The bulk of protein accumulated in the soluble fraction of the cell. Hepatic albumin and transferrin concentrations increase and

Hepatomegaly with severe steatosis in HIV-seropositive patients.

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Prijava / prijava

OBJECTIVE To describe death attributed to severe hepatomegaly and macrovesicular steatosis without inflammation or necrosis in HIV-seropositive patients without AIDS. METHODS Patients from the AIDS Clinical Trials Group (ACTG) Adverse Reactions and the Food and Drug Administration's (FDA)

Aflatoxin exposure may contribute to chronic hepatomegaly in Kenyan school children.

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Prijava / prijava

BACKGROUND Presentation with a firm type of chronic hepatomegaly of multifactorial etiology is common among school-age children in sub-Saharan Africa. OBJECTIVE Aflatoxin is a liver toxin and carcinogen contaminating staple maize food. In this study we examined its role in chronic

The rat liver microcirculation in alcohol-induced hepatomegaly.

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Prijava / prijava

It has been suggested that hepatocyte enlargement can lead to compression of the extracellular space (sinusoidal and interstitial) and induce portal hypertension. However, this hypothesis has never been tested by measuring the vascular and extravascular spaces in the intact liver. The aim of the

Liver-specific ablation of integrin-linked kinase in mice results in abnormal histology, enhanced cell proliferation, and hepatomegaly.

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Prijava / prijava

Hepatocyte differentiation and proliferation are greatly affected by extracellular matrix (ECM). Primary hepatocytes cultured without matrix dedifferentiate over time, but matrix overlay quickly restores differentiation. ECM also is critical in liver regeneration where ECM degradation and

Non-alcoholic fatty liver disease in the Philippines: comparable with other nations?

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Prijava / prijava

OBJECTIVE To evaluate the prevalence and determined the common characteristics of patients diagnosed with non-alcoholic fatty liver disease (NAFLD) at the Philippine General Hospital, Manila, from January 1999 to December 2004. METHODS NAFLD was diagnosed in 134 from a total of 1102 patients, based

Oncogene-induced liver neoplasia in transgenic mice.

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Prijava / prijava

Models of hepatocarcinogenesis were generated by directing the expression of SV40 T-antigens, an oncogenic mutant of c-H-ras, or c-myc to the liver of transgenic mice using the albumin enhancer/promoter. The majority of mice carrying the ras transgene (group A) were born with enlarged livers and

[Prognostic factors in liver tumors].

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Prijava / prijava

The prognosis of patients with hepatocellular carcinoma is dismal. Long-term survival and cure of patients with hepatocellular carcinoma (HCC) can be expected only after resection or hepatectomy followed by transplantation. Thus, prognosis primarily depends on the possibility of resective surgery,

Primary systemic amyloidosis: resolution of the nephrotic syndrome with melphalan and prednisone.

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Prijava / prijava

We describe two patients with primary systemic amyloidosis (AL) and the nephrotic syndrome. The administration of melphalan and prednisone was associated with resolution of the nephrotic syndrome. The serum albumin level returned to normal, proteinuria decreased to near normal, edema resolved, and

Influence of low levels of dietary aflatoxins on Eimeria tenella infections in broilers.

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Prijava / prijava

The present study was conducted to evaluate the adverse effects of an interaction between low levels of dietary aflatoxins (AF) and Eimeria tenella infection on broiler chicks. A set of 1-day-old chicks were raised for 35 days in the following groups: a control group, a group fed AF, a group fed AF

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