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12 rezultatov
[Contribution to the knowledge of hemoglobin. VI. Further studies on changes in hemoglobin fractions in the normal dog with posthemorrhagic hemorrhage (research with L-leucine-C-14)].
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Combined oral contraceptives affect liver mitochondrial activity.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
OBJECTIVE
To examine liver mitochondrial function in women using combined oral contraceptives (COCs) containing ethinylestradiol.
METHODS
A breath test after oral administration of 1 mg/kg (13)C-alpha-ketoisocaproic acid ((13)C-KICA) and 20 mg/kg L-leucine was performed twice: (i) in 15 women on day
Neutrophil adhesion inhibition prolongs survival of cardiac allografts with hyperacute rejection.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Hyperacute rejection results in rapid destruction of a cardiac allograft and is characterized by infiltration of neutrophils into the donor organ. We sought to ameliorate this response by using a potent inhibitor of neutrophil adhesion to vascular endothelium, NPC 15669
Neutrophil adhesion and complement inhibition prolongs survival of cardiac xenografts in discordant species.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Hyperacute rejection results in rapid destruction of a discordant cardiac xenograft and is characterized by antibody deposition, complement activation, and platelet aggregation. The importance of neutrophils is unclear. Complement inhibition prolongs discordant cardiac xenograft survival. The
The leukocyte recruitment inhibitor, NPC 15669 accelerates healing in acetic acid-induced colitis.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The therapeutic efficacy of the leukocyte recruitment inhibitor, NPC 15669 (N-[9H-(2,7-dimethylfluoren-9-yl-methoxy)carbonyl]-L-leucine), was evaluated through the time course of acetic acid colitis in rats. Intrarectal (i.r.) administration of dilute acetic acid produced intense inflammation of the
Molecular characterization of L-amino acid oxidase from Agkistrodon halys blomhoffii with special reference to platelet aggregation.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
L-Amino acid oxidase (LAO, EC 1.4.3.2) is widely distributed in snake venom, and induces apoptosis in vascular endothelial cells, causing prolonged bleeding from vessel walls at bite sites. The effect of snake venom LAOs on platelet function is controversial. Further, we have little information on
AMINO ACID MIXTURES EFFECTIVE PARENTERALLY FOR LONG CONTINUED PLASMA PROTEIN PRODUCTION. CASEIN DIGESTS COMPARED.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
When blood plasma proteins are depleted by bleeding with return of red cells suspended in saline (plasmapheresis) it is possible to bring dogs to a steady state of hypoproteinemia and a constant level of plasma protein production if the diet nitrogen intake is controlled and limited. Such dogs are
Apoxin I, a novel apoptosis-inducing factor with L-amino acid oxidase activity purified from Western diamondback rattlesnake venom.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Venom of the western diamondback rattlesnake (Crotalus atrox) induces apoptosis in human umbilical vein endothelial cells, which could result in hemorrhage in tissues bitten by the snake. To identify the hemorrhagic factor, we purified a novel protein, apoxin I, from rattlesnake venom. Apoxin I
Increased nitric oxide synthesis in uraemic platelets is dependent on L-arginine transport via system y(+)L.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Bleeding tendency in uraemic patients seems to be related to alterations in the activity of the L-arginine-nitric oxide (NO) signalling pathway in platelets. We have reported previously that L-arginine influx into human platelets is mediated by the high-affinity cationic amino acid transport system
Molecularly designed surfaces for blood deheparinization using an immobilized heparin-binding peptide.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Systemic heparinization, used during haemodialysis to prevent blood clotting on the extracorporeal circuit, leads to a high incidence of hemorrhagic complications. The adverse reactions associated with heparin neutralization using protamine sulphate justify the development of an alternative system
Inhibition of human leukocyte elastase by N-substituted peptides containing alpha,alpha-difluorostatone residues at P1.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
A series of tripeptides which contain alpha,alpha-difluorostatone residues at P1-P1' and span the S3-S1' subsites have been shown to be potent inhibitors of human leukocyte elastase (HLE). The tripeptides described contain the nonproteinogenic achiral residue N-(2,3-dihydro-1H-inden-2-yl)glycine at
Isolation, structural, and functional characterization of an apoptosis-inducing L-amino acid oxidase from leaf-nosed viper (Eristocophis macmahoni) snake venom.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The enzyme L-amino acid oxidase (LAO) from the leaf-nosed viper (Eristocophis macmahoni) snake venom was purified to homogeneity in a single step using high performance liquid chromatography on a Nucleosil 7C18 reverse phase column. The molecular mass of the purified enzyme was 58734.0 Da, as
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