lymphoproliferative disorders/nikotin

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[The role of nicotine in regulation of lymphocyte proliferation].

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Prijava / prijava

The effect of nicotine on both the expression of nicotinic acetylcholine receptors (nAChRs) and proliferation of hybridoma cells and normal mouse lymphocytes has been investigated. By means of immunoenzyme assay, nicotine was shown to regulate the number of nAChRs in both hybridoma cells and normal

[The dog as a model for comparative studies of lymphoma and leukemia in humans].

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Prijava / prijava

Dogs have accompanied humankind for thousands of years. They share the same environment, and thus are exposed to the same environmental factors such as air pollution, tobacco smoke, and various chemicals. Recent development of veterinary care has led to a significant extension of dogs' lifespan and

Increased incidence of oropharyngeal squamous cell carcinomas after liver transplantation for alcoholic cirrhosis.

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Prijava / prijava

BACKGROUND THE aim of this study was to describe the features of posttransplantation tumors observed in a series of liver transplant recipients with special reference to patients receiving a transplant for alcoholic cirrhosis. METHODS Among 171 consecutive liver transplant recipients, 90 patients

Second lung malignancy and Richter syndrome in chronic lymphocytic leukemia: case report and literature review.

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Prijava / prijava

BACKGROUND Chronic lymphocytic leukemia (CLL) is the most frequent lymphoproliferative disease. Transformation into Richter disease and occurrence of second malignancies involving the lungs are rare complications. The hallmarks of any thoracic involvement are still unknown. METHODS We report a case

Coexistence of lymphoproliferative and myeloproliferative neoplasms with simultaneous CALR and JAK2 V617F mutations.

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Prijava / prijava

BACKGROUND Hematopoietic malignancies are a group of blood cell disorders characterized by abnormal hematopoietic proliferation. OBJECTIVE The identification of specific clinicopathologic characteristics and tumor-related gene status provides critical information on potential therapeutic

Cutaneous and Mucosal Manifestations of Sjögren's Syndrome.

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Prijava / prijava

Sjögren's syndrome is currently considered an "autoimmune epithelitis," as exocrine glands, especially salivary and lacrimal, are progressively destructed by an immune-mediated process associated with specific serum autoantibodies and local lymphocyte infiltrate. Xerostomia remains a key complain in

Incidence, risk factors and outcomes of de novo malignancies post liver transplantation.

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Prijava / prijava

Liver transplantation (LT) is associated with a 2 to 7 fold higher, age and gender adjusted, risk of de novo malignancy. The overall incidence of de novo malignancy post LT ranges from 2.2% to 26%, and 5 and 10 years incidence rates are estimated at 10% to 14.6% and 20% to 32%, respectively. The

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