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Stran 1 iz 79 rezultatov
Effect of cyclophosphamide on serum ceruloplasmin oxidase activity in sarcoma bearing rats.
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Prijava / prijava
High levels of serum ceruloplasmin oxidase activity were detected in U strain isogenic male rats bearing a syngeneic sarcoma in all phases of tumoral evolution. Normal levels of ceruloplasmin were only observed after a single i.p. dose of cyclophosphamide (100 mg/kg). However subsequent weekly
Lysyl oxidase is downregulated by the EWS/FLI1 oncoprotein and its propeptide domain displays tumor supressor activities in Ewing sarcoma cells.
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Ewing sarcoma is the second most common bone malignancy in children and young adults. It is driven by oncogenic fusion proteins (i.e. EWS/FLI1) acting as aberrant transcription factors that upregulate and downregulate target genes, leading to cellular transformation. Thus, identificating these
[Activity of monoamine oxidase and diamine oxidase in a culture of chick fibroblasts infected with Rous sarcoma virus].
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Effect of podophyllotoxin, alpha-peltatin and beta-peltatin on the cytochrome oxidase activity of sarcoma 37.
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[Monoamine oxidase activity in cell nuclei and nuclear fractions of mouse liver under normal conditions and during development of ascitic sarcoma 37].
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HISTOCHEMISTRY OF KAPOSI'S SARCOMA. II. CHOLINESTERASES, MONOAMINE OXIDASE, AND ADENOSINE TRIPHOSPHATASE.
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Enzyme changes induced in normal and malignant tissues with chemical agents. VI. Effect of acetylpodophyllotoxin-omega-pyridinium chloride on malic-oxidase and on isocitric-oxidase systems of sarcoma 37.
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Enzyme changes induced in normal and malignant tissues with chemical agents. III. Effect of acetylpodophyllotoxin-omega-pyridinium chloride on cytochrome oxidase, cytochrome c, succinoxidase, succinic dehydrogenase, and respiration of sarcoma 37.
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Effects of glutamate dehydrogenase, choline oxidase, and glucose-6-phosphatase on 67Ga accumulation in lysosome.
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OBJECTIVE
To clarify the effects of the activities of hepatic enzymes in liver, hepatoma, and malignant tumor on 67Ga accumulation in lysosome.
METHODS
67Ga-citrate solution was prepared from carrier-free 67Ga-citrate solution 0.08 mol.L-1 and sodium citrate solution 0.08 mol.L-1, and was injected
Diamine oxidase and polyamine oxidase activities in normal and transformed cells.
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1. The activity of diamine oxidase (EC 1.4.3.6) in normal rat kidney cells and in normal rat kidney cells transformed by avian sarcoma virus (B77 strain) growing in tissue culture varies with the stage of growth. There is an initial stimulation of activity by 24h after seeding, followed by a steep
Effect of microinjected amine and diamine oxidases on the ultrastructure of eukaryotic cultured cells.
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Diamine oxide and serum amine oxidase, which catalyse the oxidation of diamines and polyamines, respectively, were trapped within reconstituted Sendai virus envelopes. These loaded envelopes were incubated with cultured normal chick fibroblasts or with fibroblasts transformed by Rous sarcoma
Deficient production of lysyl oxidase in cultures of malignantly transformed human cells.
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Prijava / prijava
Lysyl oxidase activity in the culture medium of eight malignantly transformed human cell lines was very low compared with that in four control fibroblast lines, being 9-16% in five sarcoma cell lines and 7-11% in three other tumour cell lines. The low enzyme activity was probably due to deficient
Modification of diamine oxidase activity in vitro by metabolites of asparagine and differences in asparagine decarboxylation in normal and virus-transformed baby hamster kidney cells.
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1. The oxidation of putrescine in vitro by pig kidney diamine oxidase (EC 1.4.3.6) was increased in the presence of 2-oxosuccinamic acid and malonamic acid. 2. It was inhibited by 3-aminopropionamide, oxaloacetate and pyruvate. 3. 2-Oxosuccinamate was derived from asparagine in virus-transformed
Molecular determinants of cytochrome C oxidase IV mRNA axonal trafficking.
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In previous studies, we identified a putative 38-nucleotide stem-loop structure (zipcode) in the 3' untranslated region of the cytochrome c oxidase subunit IV (COXIV) mRNA that was necessary and sufficient for the axonal localization of the message in primary superior cervical ganglion (SCG)
Involvement of RAGE, NADPH oxidase, and Ras/Raf-1 pathway in glycated LDL-induced expression of heat shock factor-1 and plasminogen activator inhibitor-1 in vascular endothelial cells.
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Atherothrombotic cardiovascular diseases are the predominant causes of mortality of diabetic patients. Plasminogen activator inhibitor-1 (PAI-1) is the major physiological inhibitor for fibrinolysis, and it is also implicated in inflammation and tissue remodeling. Increased levels of PAI-1 and
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