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6 rezultatov
P-cresol, a uremic toxin, decreases endothelial cell response to inflammatory cytokines.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
Infectious diseases are among the most morbid events in uremia. The uremic toxin p-cresol may play a role in the immunodeficiency of uremia by depressing phagocyte functional capacity. Leukocyte adhesion to endothelium, a key event in the immune response, is mediated by endothelial
Cytotoxic effects of p-cresol in renal epithelial tubular cells.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
The uremic syndrome is characterized by a deterioration of kidney function due to the accumulation of uremic toxins. Currently, 100 different uremic toxins have been identified. Uremic toxins are particularly difficult to remove by conventional dialysis treatments and are the major causes
Effects of AST-120 on blood concentrations of protein-bound uremic toxins and biomarkers of cardiovascular risk in chronic dialysis patients.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
Removal of protein-bound uremic toxins by dialysis therapy is limited. The effect of oral adsorbent AST-120 in chronic dialysis patients has rarely been investigated.
METHODS
AST-120 was administered 6.0 g/day for 3 months in 69 chronic dialysis patients. The blood concentrations of
Impaired intestinal barrier function in a mouse model of hyperuricemia.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Previous studies have demonstrated the effects of hyperuricemia on the damage to target organs, including the kidneys, joints and the heart. However, it is unclear whether hyperuricemia results in damage to the intestines. The aim of the present study was to investigate intestinal barrier
The association of uremic toxins and inflammation in hemodialysis patients.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
Cardiovascular disease is the leading cause of mortality in hemodialysis patients and is associated with chronic inflammation. Elevation of uremic toxins, particular protein-bound uremic toxins, is a possible cause of hyper-inflammation in hemodialysis patients. But the association
Does uremia cause vascular dysfunction?
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Vascular dysfunction induced by uremia has 4 main aspects. (1) Atherosclerosis is increased. Intima-media thickness is increased, and animal studies have established that uremia accelerates atherosclerosis. Uremic toxins are involved in several steps of atherosclerosis. Leukocyte activation is
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