15 rezultatov
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present disclosure generally relates to the production and/or therapeutic use of recombinant type 1 ribosome inhibiting proteins for the treatment of cancer and infectious diseases.
2. Description of the Relevant Art
Ribosome Inactivating
BACKGROUND
The present invention relates, in general, to materials useful as components of cytotoxic therapeutic agents. More particularly, the invention relates to analogs of ribosome-inactivating proteins specifically modified for conjugation to targeting molecules and to polynucleotides encoding
FIELD OF THE INVENTION
The present invention generally relates to materials useful as components of cytotoxic therapeutic agents. More particularly, the invention relates to ribosome-inactivating proteins, to analogs of ribosome-inactivating proteins, to polynucleotides encoding such proteins and
FIELD OF THE INVENTION
The present invention generally relates to materials useful as components of cytotoxic therapeutic agents. More particularly, the invention relates to ribosome-inactivating proteins, to analogs of ribosome-inactivating proteins, to polynucleotides encoding such proteins and
FIELD OF THE INVENTION
The present invention generally relates to materials useful as components of cytotoxic therapeutic agents. More particularly, the invention relates to ribosome-inactivating proteins, to analogs of ribosome-inactivating proteins, to polynucleotides encoding such proteins and
FIELD OF THE INVENTION
The present invention generally relates to materials useful as components of cytotoxic therapeutic agents. More particularly, the invention relates to ribosome-inactivating proteins, to analogs of ribosome-inactivating proteins, to polynucleotides encoding such proteins and
FIELD OF THE INVENTION
The present invention generally relates to materials useful as components of cytotoxic therapeutic agents. More particularly, the invention relates to ribosome-inactivating proteins, to analogs of ribosome-inactivating proteins, to polynucleotides encoding such proteins and
BACKGROUND
The present invention relates, in general, to materials useful as components of cytotoxic therapeutic agents. More particularly, the invention relates to polynucleotides encoding ribosome-inactivating proteins, to polynucleotides encoding analogs of ribosome-inactivating proteins
FIELD OF THE INVENTION
The present invention relates to the isolation and characterization of a novel ribosome-inactivating protein from the plant Bryonia dioica. The oligonucleotide sequence encoding the protein and its amino acid sequence have been determined. The invention also relates to
FIELD OF THE INVENTION
The invention discloses a new type-1 ribosome-inactivating protein (RIP), referred to as bouganin, isolated from the leaves of Bougainvillea species, especially B. spectabilis Willd. Bouganin differs from other type-1 RIP by its unique amino acid composition. Bouganin has a
FIELD OF THE INVENTION
The invention discloses a new type-1 ribosome-inactivating protein (RIP), referred to as bouganin, isolated from the leaves of Bougainvillea species, especially B. spectabilis Willd. Bouganin differs from other type-1 RIP by its unique amino acid composition. Bouganin has a
This invention relates to the use of particular conjugates which are targeted to inhibit cell proliferation, and more specifically, to the use of fibroblast growth factor conjugated to a cytotoxic agent.
BACKGROUND OF THE INVENTION
Angiogenesis plays a critical role in embryonic development and in
The present invention generally relates to materials useful as components of cytotoxic therapeutic agents. More particularly, the invention relates to ribosome-inactivating proteins, to analogs of ribosome-inactivating proteins, to polynucleotides encoding such proteins and analogs, some of which
FIELD OF THE INVENTION
The present invention generally relates to materials useful as components of cytotoxic therapeutic agents. More particularly, the invention relates to ribosome-inactivating proteins, to analogs of ribosome-inactivating proteins, to polynucleotides encoding such proteins and
This application claims priority under 35 U.S.C. .sctn.119(a) (d) to Chinese patent application serial number 00119553.0, filed on Aug. 2, 2000 and Chinese patent application serial number 001103102.6, filed on Jan. 18, 2001.
FIELD OF THE INVENTION
This invention relates to mutant trichosanthin