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succinic acid/hypoxia
Povezava se shrani v odložišče
Stran 1 iz 40 rezultatov
[Protective effect of succinic acid on primary cardiomyocyte hypoxia/reoxygenation injury].
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Prijava / prijava
To establish cardiomyocyte hypoxia/reoxygenation injury model by culturing primary cardiomyocytes from suckling SD rats, in order to study the effect of succinic acid on LDH leakage rate cardiomyocyte ischemia/reperfusion injury. Furthermore, flow cytometry and western blot were conducted to detect
[The answer reaction of system complement on correction of hypoxia of hydazepam and succinic acid].
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Investigated functionally activation of human complement in vivo an model of high hypoxia (6-7,5 km) as without correction, so at the phone of medicine hydazepam and succinic acid. Discover that by analysis of the sensitive to complement components one can estimate effects of high hypoxia and her
[The effect of an extract of Baikal skullcap (Scutelleria baicalensis) on succinic acid oxidation by the brain mitochondria in rats with hypoxia].
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Oxidative phosphorylation in the mitochondria of rat brain in normobaric hypercapnic hypoxia and preventive administration of Scutellaria baicalensis extract was studied by polarography. Hypoxia causes diminution of energy of the rat brain mitochondria with separation of oxidative phosphorylation
[Succinic acid and anoxia].
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[Effect of salts of succinic acid and ethiron on circulatory-respiratory hypoxia].
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[Effect of a drug isolated from the heart on the bioenergetics of cardiomyocytes in hypoxia and ischemia].
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Prijava / prijava
It has been established that cordialin inhibits selectively succinic acid oxidation and intensifies the exudation of a NADH2 substrate which is energetically more advantageous, and in this way has a favorable effect on energy metabolism, evidence of which is increase of the ATP content in the
Tissue-Specific Peculiarities of Vibration-Induced Hypoxia in Rabbit Liver and Kidney.
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Prijava / prijava
Activity of the energy production systems in rabbit liver and kidney under conditions of unfavorable vibration exposure was studied by the polarography method using a galvanic-type closed oxygen sensor. The rate of oxidation of endogenous substrates by mitochondria was determined by the tissue and
GABA metabolism is crucial for long-term survival of anoxia in annual killifish embryos
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Prijava / prijava
In most vertebrates, a lack of oxygen quickly leads to irreparable damages to vital organs, such as the brain and heart. However, there are some vertebrates that have evolved mechanisms to survive periods of no oxygen (anoxia). The annual killifish (Austrofundulus limnaeus) survives in
Exogenous GABA is quickly metabolized to succinic acid and fed into the plant TCA cycle.
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Exogenous application of γ-aminobutyric acid (GABA) could improve plant tolerance to environmental stresses such as hypoxia, heat, cold, drought, and salt stress. However, the mechanism by which GABA relieves stress is poorly understood. Here, we studied the uptake and metabolism of exogenous GABA
[Intermittent hypoxic training and L-arginine as corrective agents for myocardial energy supply under acute hypoxia].
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Prijava / prijava
It NO has been shown play to the primary role in several mitochondrial functions. Our aim for this study was to investigate whether exogenous NO (L-arginine) or NO blocker L-NNA modulated the adaptive reactions of rat myocardial tissue respiration on intermittent hypoxic training (IHT). In the
[Antihypoxic effect of 3-hydroxypyridine and succinic acid derivatives and their nootropic action in alloxan diabetes].
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Prijava / prijava
Relationship between the antihypoxic effect of 3-hydroxypyridine and succinic acid derivatives (emoxipine, reamberin and mexidol) and their effect on conditional learning, glycemia, and lipidemia was studied in rats with alloxan-induced diabetes. In parallel, the analogous relationship was
[Investigation of the antioxidant activity and cardioprotective effect of reamberin and cytoflavin in newborn rats exposed to chronic hemic hypoxia].
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The authors analyzed the antioxidant activity of reamberin and cytoflavin and evaluated their cardioprotective effect, by investigating lipid peroxidation and oxidative modification of plasma proteins, as well as the ultrastructure of newborn rat cardiomyocytes under chronic hemic hypoxia induced by
[Krebs cycle in tissue of rats subjected to combined effect of hypercapnia, hypoxia and cooling].
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The content of the Krebs cycle substrates and activity of dehydrogenases corresponding to them were studied in the brain and myocardium tissues of the non-linear male rats adapted to acute hypoxia under conditions of the altered gas medium. The content of malate and succinic acid was studied in the
Antihypoxic and antioxidant effects of exogenous succinic acid and aminothiol succinate-containing antihypoxants.
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Pronounced antihypoxic and antioxidant effects of preventive injection of succinic acid, aminothiol antihypoxants gutimine and amtizol, and succinate-containing aminothiol antihypoxants gutimine succinate and amtizol succinate to Wistar rats with acute hypoxic hypoxia have been demonstrated.
Effects of a Preparation Containing Pantogam, Succinic Acid, and Chitosan on Activities of the Glutathione System and NADPH-Generating Enzymes in Rat Tissues under Conditions of Cerebral Ischemia/Reperfusion.
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Prijava / prijava
Treatment with the complex preparation containing pantogam, succinic acid, and chitosan normalized the concentration of reduced glutathione and activities of glutathione peroxidase, glutathione reductase, and some NADPH-generating enzymes (glucose-6-phosphate dehydrogenase and NADPH-isocitrate
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