taxus/kalij

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Hypertonic sodium bicarbonate for Taxus media-induced cardiac toxicity in swine.

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Prijava / prijava

OBJECTIVE To determine whether intravenous (IV) hypertonic sodium bicarbonate is effective in the reversal of QRS widening associated with severe Taxus intoxication. METHODS Seventeen anesthetized and instrumented swine were poisoned with an IV extract of Taxus media until doubling of the QRS

Efficient paclitaxel production using protoplasts isolated from cultured cells of Taxus cuspidata.

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Prijava / prijava

Efficient isolation of protoplasts from Taxus cuspidata cultured cells, localization of paclitaxel in the cultured cells, and efficient production of paclitaxel by protoplasts were studied. Hemicellulase, potassium citric acid solution, and degassing treatments were effective in increasing the yield

Optimization of an HPLC Method for Determining the Genomic Methylation Levels of Taxus Cells.

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Prijava / prijava

An HPLC method for quantifying total DNA methylation in Taxus chinensis cells is described. Optimal conditions for the method were established as follows: DNA was hydrolyzed with DNA degradase at 37°C for 3 h. The mobile phase was a mixture of Solvent A [50 mM potassium dihydrogen

Gateways to clinical trials.

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Prijava / prijava

5-Methyltetrahydrofolate, (R)-flurbiprofen; Ad5CMV-p53, adalimumab, alefacept, alemtuzumab, Alequel, alicaforsen sodium, almotriptan, anakinra, aprepitant, aripiprazole, armodafinil; Bevacizumab, bortezomib, bosentan; Canfosfamide hydrochloride, ciclesonide, clofarabine, Cypher; Darbepoetin alfa,

[Electrophysiology of the mechanisms of action of the yew toxin, taxine, on the heart].

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Prijava / prijava

The effects of the sulfate salt of taxine, the alkaloid mixture of the yew (Taxus baccata L.), on membrane currents of enzymatically isolated single ventricular cells of guinea pig were studied under current- or voltage clamp conditions. It was found that the drug inhibits both the sodium (INa) and

Gateways to clinical trials.

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Prijava / prijava

(+)-Dapoxetine hydrochloride, (R)-Etodolac; Abatacept, ABT-510, Adalimumab, Agatolimod sodium, Alemtuzumab, Alvocidib hydrochloride, Aminolevulinic acid methyl ester, Aripiprazole, AS01B, AS02B, AS02V, Azacitidine; Becatecarin, Bevacizumab, Bevirimat, Bortezomib, Bremelanotide; CAIV-T, Canfosfamide

Gateways to clinical trials.

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Prijava / prijava

Gateways to Clinical Trials are a guide to the most recent clinical trials in current literature and congresses. The data in the following tables has been retrieved from the Clinical Trials Knowledge Area of Prouse Science Integrity, the drug discovery and development portal,

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