Slovenian
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)
Stran 1 iz 1081 rezultatov
Thymidine phosphorylase expression correlates with tumor differentiation and Bcl-2 in invasive breast cancer.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
Angiogenesis plays an important role in the growth and metastasis of solid tumors. Several angiogenic factors have been identified, and thymidine phosphorylase (TP) is thought to be one such factor. To date, little information is available on the relationship between TP and other
Feasibility of thymidine labelling index on fine needle aspirates from breast cancer: comparison with surgical samples.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Fine-needle aspiration (FNA) provides a suitable diagnostic tool in the management of patients with breast cancer lesions. The current study reports on tumor proliferative activity, by 3H-Thymidine Labelling Index (TLI), assessed on 59 FNA (TLI1) and 28 surgical specimens (TLI2) from the same breast
Is the thymidine labeling index a good prognostic marker in breast cancer?
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
The aim of the present study was to determine the prognostic relevance of thymidine labeling index (TLI) in patients with breast cancer.
METHODS
TLI of the primary tumor was measured in 268 patients at the time of the surgical biopsy by an in vitro method.
RESULTS
Fifty-four patients had
Proliferative activity of primary breast cancer and of synchronous lymph node metastases evaluated by [3H]-thymidine labelling index.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The [3H]-thymidine labelling index ([3H]TdR LI) has been used to evaluate and comparatively analyse the proliferative activity of different tumour lesions from the same patient. The analysis was performed on the primary tumour and its synchronous lymph node metastasis from 210 patients operated on
Prognostic impact of thymidine phosphorylase expression in breast cancer--comparison of microarray and immunohistochemical data.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Contrary findings exist according to the prognostic and predictive impact of thymidine phosphorylase (TP) expression in breast cancer. Goal of our study was to investigate TP expression on the mRNA level by microarray analysis in a large cohort of 1781 breast cancers and to analyse its prognostic
Serum thymidine kinase 1 levels predict cancer-free survival following neoadjuvant, surgical and adjuvant treatment of patients with locally advanced breast cancer.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
In this study, the use of serum thymidine kinase 1 protein (STK1p) concentration for the prognosis of the overall survival of patients with locally advanced breast cancer (n=51) following routine treatment (neoadjuvant treatment, surgery and chemotherapy) was investigated. The patients were followed
Early prediction of pathologic response to neoadjuvant treatment of breast cancer: use of a cell-loss metric based on serum thymidine kinase 1 and tumour volume
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Background: After neoadjuvant chemotherapy of breast cancer pathologic complete response (pCR) indicates a favorable prognosis. Among non-selected patients, pCR is, however, achieved in only 10-30%. Early evaluation of tumour response to treatment would facilitate
Comparison of diagnostic and prognostic performance of two assays measuring thymidine kinase 1 activity in serum of breast cancer patients.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
We compared two recently developed immunoassays for serum thymidine kinase 1 (TK1) activity: one manual assay (DiviTum, Biovica(®)) and one fully automated assay (Liaison, Diasorin(®)).
METHODS
The study included 368 women: 149 healthy blood donors (control), 59 patients with benign
Thymidine kinase in breast cancer.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The enzyme thymidine kinase is associated with DNA synthesis. Thymidine kinase serum levels were studied in normal controls (n = 20), patients with primary breast cancer (n = 60), patients with systemic breast cancer (n = 20) and as a non-cancer disease control group in patients with inflammatory
Can thymidine kinase levels in breast tumors predict disease recurrence?
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
BACKGROUND
Our previous study of thymidine kinase (TK) levels in the serum of breast cancer patients demonstrated a statistically significant positive correlation with cancer stage. In postsurgical follow-up studies of 20 patients with primary breast cancer, total serum TK levels rose with disease
[An uncommon form of thymidine kinase in breast cancers].
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
An unusual form of thymidine kinase has been found in cytosols from breast cancers. It differs from the adult and fetal isoenzymes of thymidine kinase in so far as its activity could not be isolated from that of thymidylate kinase. Following sucrose density gradients, electrofocusing, ion exchange
Progestin stimulation of thymidine kinase in the human breast cancer cell line T47D.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Our laboratory has previously reported that progestins stimulate growth of the human breast cancer cell line T47D. In an attempt to probe further into this stimulation, we are investigating progestin effects on thymidine kinase (EC 2.7.1.21), an enzyme known to be involved in growth regulation. This
Enhancement of hormonal synchronization and 5-fluorouracil cytotoxicity in breast cancer cells by low concentration of thymidine.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
A method is described that applies a low concentration of thymidine to achieve maximal hormonal synchronization in cultures of an established human breast cancer cell line, MCF-7. The method consists of sequential treatments with tamoxifen, estradiol, and thymidine. The increase (3.8 fold) in the
Local regression of breast tumors following intramammary ganciclovir administration in double transgenic mice expressing neu oncogene and herpes simplex virus thymidine kinase.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
Females from a mouse lineage transgenic for the activated rat neu oncogene under the control of the mouse mammary tumor virus (MMTV) long terminal repeat (LTR) all develop breast tumors with high reproducibility within the first 2-3 months of life. These animals were crossed with mice from a lineage
Differential chemosensitivity of breast cancer cells to ganciclovir treatment following adenovirus-mediated herpes simplex virus thymidine kinase gene transfer.
Samo registrirani uporabniki lahko prevajajo članke
Prijava / prijava
The development of resistance to radiation and chemotherapeutic agents that cause DNA damage is a major problem for the treatment of breast and other cancers. The p53 tumor suppressor gene plays a direct role in the signaling of cell cycle arrest and apoptosis in response to DNA damage, and p53 gene
Najbolj popolna baza zdravilnih zelišč, podprta z znanostjo
- Deluje v 55 jezikih
- Zeliščna zdravila, podprta z znanostjo
- Prepoznavanje zelišč po sliki
- Interaktivni GPS zemljevid - označite zelišča na lokaciji (kmalu)
- Preberite znanstvene publikacije, povezane z vašim iskanjem
- Iščite zdravilna zelišča po njihovih učinkih
- Organizirajte svoje interese in bodite na tekočem z raziskavami novic, kliničnimi preskušanji in patenti
Vnesite simptom ali bolezen in preberite o zeliščih, ki bi lahko pomagala, vnesite zelišče in si oglejte bolezni in simptome, proti katerim se uporablja.
* Vse informacije temeljijo na objavljenih znanstvenih raziskavah
