[Lymphedema: which drug therapy?].

Treatment of primary or secondary lymphedema includes essentially complex decongestive physiotherapy. For many years now, drugs active in reducing volume of lymphedema are prospected. But few studies are available. Only few drugs have been tested. Diuretics have been the first to be used with short and brief efficacy. Benzopyrones were the most tested product with encouraging but conflicting results. New treatments are proposed without randomized controlled studies. Prevention of lymphedema remains essential in particular after treatment of breast cancer.