Journal of Oncology 2019
The Protective Effect of Dietary Phytosterols on Cancer Risk: A Systematic Meta-Analysis.
Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
Lidhja ruhet në kujtesën e fragmenteve
Fjalë kyçe
Abstrakt
Methods
We performed a literature search of PUBMED, EMBASE, CNKI, and Wanfang, and studies published before May 2019 focusing on dietary total phytosterols, β-sitosterol, campesterol, stigmasterol, β-sitostanol, and campestanol, as well as their relationships with cancer risk, were included in this meta-analysis. Summaries of the relative risks from 11 case-control and case-cohort studies were eventually estimated by randomized or fixed effects models.Results
The summary relative risk for the highest versus the lowest intake was 0.63 (95% confidence interval [CI] = 0.49-0.81) for total phytosterols, 0.74 (95% CI = 0.54-1.02) for β-sitosterol, 0.72 (95% CI = 0.51-1.00) for campesterol, 0.83 (95% CI = 0.60-1.16) for stigmasterol, 1.12 (95% CI = 0.96-1.32) for β-sitostanol, and 0.77 (95% CI = 0.65-0.90) for campestanol. In a dose-response analysis, the results suggested a linear association for campesterol and a nonlinear association for total phytosterol intake.