Faqja 1 nga 32 rezultatet
BACKGROUND OF THE INVENTION
This invention relates to a series of guanidine derivatives characterized by an (aryloxy or arylamino) alkyl substituent. In particular, this invention relates to guanidine derivatives useful as anti-inflammatory agents.
Substituted guanidines are known in the art. U.S.
FIELD OF THE INVENTION
The invention provides inhibitors of F.sub.1F.sub.0-ATPases (e.g., mitochondrial F.sub.1F.sub.0-ATPases) and their therapeutic use. In particular, the invention provides saturated acyl guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using saturated acyl
FIELD OF THE INVENTION
The invention provides inhibitors of F.sub.1F.sub.0-ATPases (e.g., mitochondrial F.sub.1F.sub.0-ATPases) and their therapeutic use. In particular, the invention provides pyrazolyl guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using pyrazolyl guanidine
FIELD OF THE INVENTION
The invention provides inhibitors of F.sub.1F.sub.0-ATPases (e.g., mitochondrial F.sub.1F.sub.0-ATPases) and their therapeutic use. In particular, the invention provides pyrazolyl guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using pyrazolyl guanidine
FIELD OF THE INVENTION
The invention provides inhibitors of F.sub.1F.sub.0-ATPases (e.g., mitochondrial F.sub.1F.sub.0-ATPases) and their therapeutic use. In particular, the invention provides pyrazolyl guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using pyrazolyl guanidine
FIELD OF THE INVENTION
The invention provides inhibitors of F.sub.1F.sub.0-ATPases (e.g., mitochondrial F.sub.1F.sub.0-ATPases) and their therapeutic use. In particular, the invention provides pyrazolyl guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using pyrazolyl guanidine
FIELD OF THE INVENTION
The invention provides inhibitors of F.sub.1F.sub.0-ATPases (e.g., mitochondrial F.sub.1F.sub.0-ATPases) and their therapeutic use. In particular, the invention provides cycloalkyl guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using cyclalkyl guanidine
FIELD OF THE INVENTION
The invention provides inhibitors of F.sub.1F.sub.0-ATPases (e.g., mitochondrial F.sub.1F.sub.0-ATPases) and their therapeutic use. In particular, the invention provides pyridonyl guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using pyridonyl guanidine
FIELD OF THE INVENTION
The invention provides inhibitors of F.sub.1F.sub.0-ATPases (e.g., mitochondrial F.sub.1F.sub.0-ATPases) and their therapeutic use. In particular, the invention provides indazole guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using indazole guanidine
FIELD OF THE INVENTION
The invention provides inhibitors of F.sub.1F.sub.0-ATPases (e.g., mitochondrial F.sub.1F.sub.0-ATPases) and their therapeutic use. In particular, the invention provides pyridonyl guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using pyridonyl guanidine
FIELD OF THE INVENTION
The invention provides inhibitors of F.sub.1F.sub.0-ATPases (e.g., mitochondrial F.sub.1F.sub.0-ATPases) and their therapeutic use. In particular, the invention provides heterocyclic guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using heterocyclic
FIELD OF THE INVENTION
The invention provides inhibitors of F.sub.1F.sub.0-ATPases (e.g., mitochondrial F.sub.1F.sub.0-ATPases) and their therapeutic use. In particular, the invention provides trifluoromethyl pyrazolyl guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using
FIELD OF THE INVENTION
The invention provides inhibitors of F.sub.1F.sub.0-ATPases (e.g., mitochondrial F.sub.1F.sub.0-ATPases) and their therapeutic use. In particular, the invention provides trifluoromethyl pyrazolyl guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using
FIELD OF THE INVENTION
The invention provides inhibitors of F.sub.1F.sub.0-ATPases (e.g., mitochondrial F.sub.1F.sub.0-ATPases) and their therapeutic use. In particular, the invention provides trifluoromethyl pyrazolyl guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using
FIELD OF THE INVENTION
The invention provides inhibitors of F.sub.1F.sub.0-ATPases (e.g., mitochondrial F.sub.1F.sub.0-ATPases) and their therapeutic use. In particular, the invention provides pyrazolyl guanidine compounds that inhibit F.sub.1F.sub.0-ATPase, and methods of using pyrazolyl guanidine