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inflammation/vomiting
Lidhja ruhet në kujtesën e fragmenteve
Faqja 1 nga 127 rezultatet
Treatment of emesis with morpholine tachykinin receptor antagonists
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Identifikohuni Regjistrohu
SUMMARY OF THE INVENTION
This invention is concerned with novel compounds represented by structural formula I: ##STR2## wherein R.sup.2, R.sup.3, R.sup.6, R.sup.7, R.sup.8, R.sup.11, R.sup.12, R.sup.13, A, B, p, Y and Z are hereinafter defined.
The invention is also concerned with pharmaceutical
Pharmaceutical agents for the treatment of emesis
Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
BACKGROUND OF THE INVENTION
The present invention relates to a novel process for preparing and resolving 3-amino-2-phenylpiperidine and for synthesizing from the enantiomers of such compound certain pharmaceutically active substituted 2-phenyl-3-benzylaminopiperidines. The substituted
Benzoimidazole derivatives and pharmaceutical composition comprising the same
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Identifikohuni Regjistrohu
TECHNICAL FIELD
The present invention relates, in general, to novel benzoimidazole derivatives and, more particularly, to novel benzoimidazole derivatives functioning as antagonists to a vanilloid receptor (capsaicin receptor; Transient Receptor Potential Channel, Vanilloid subfamily member 1;
Azabicyclic amine derivatives and their use as therapeutic agents
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Identifikohuni Regjistrohu
CROSS REFERENCE TO RELATED APPLICATIONS
This application claims priority under 35 U.S.C. .sctn.119 from GB Application No. 0108971.3, filed Apr. 10, 2001.
The present invention provides compounds of the formula (I): ##STR2##
wherein X represents hydrogen or a C.sub.1-4 alkyl group optionally
Tetrahydropyran derivatives and their use as therapeutic agents
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Identifikohuni Regjistrohu
This invention relates to a class of tetrahydropyran compounds which are useful as tachykinin antagonists. More particularly, the compounds of the invention are useful as neurokinin 1 (NK-1) receptor antagonists.
By virtue of their excellent specificity for the human NK-1 receptor, the compounds of
Morpholine derivatives and their use as therapeutic agents
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Identifikohuni Regjistrohu
This invention relates to a class of morpholine derivatives which are useful as tachykinin antagonists.
The tachykinins are a group of naturally occurring peptides found widely distributed throughout mammalian tissues, both within the central nervous system and in peripheral nervous and circulatory
Benzoamide piperidine containing compounds and related compounds
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Identifikohuni Regjistrohu
The present invention relates to certain benzoamide piperidine containing compounds and related compounds that exhibit activity as NK-1 receptor antagonists, (e.g., substance P receptor antagonists), to pharmaceutical compositions containing them, and to their use in the treatment and prevention of
Polynucleotides that encode the calcitonin gene-related peptide receptor coponent factor (HOUNDC44)
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Identifikohuni Regjistrohu
FIELD OF THE INVENTION
This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists
Modulation of substance P by compounds containing calcium sulfate and methods relating thereto
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Identifikohuni Regjistrohu
TECHNICAL FIELD
The present invention relates generally to a method of modulating substance P by compounds containing calcium sulfate, particularly syngenite, gorgeyite and gypsum, and more specifically, to the synthesis of such compounds as well as their use to treat a variety of conditions
Therapeutic agents useful for treating pain
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Identifikohuni Regjistrohu
1. FIELD OF THE INVENTION
The present invention relates to Cyanoiminopiperazine Compounds, compositions comprising an effective amount of a Cyanoiminopiperazine Compound and methods for treating or preventing pain, urinary incontinence (UI), an ulcer, inflammatory-bowel disease (IBD),
Therapeutic agents useful for treating pain
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Identifikohuni Regjistrohu
1. FIELD OF THE INVENTION
The present invention relates to Cyanoiminopiperazine Compounds, compositions comprising an effective amount of a Cyanoiminopiperazine Compound and methods for treating or preventing pain, urinary incontinence (UI), an ulcer, inflammatory-bowel disease (IBD),
Therapeutic agents useful for treating pain
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Identifikohuni Regjistrohu
1. FIELD OF THE INVENTION
The present invention relates to 3-substituted Pyridyl Compounds, compositions comprising an effective amount of a 3-substituted Pyridyl Compound and methods for treating or preventing a condition such as pain comprising administering to an animal in need thereof an
Therapeutic agents useful for treating pain
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Identifikohuni Regjistrohu
1. FIELD OF THE INVENTION
The present invention relates to 3-substituted Pyridyl Compounds, compositions comprising an effective amount of a 3-substituted Pyridyl Compound and methods for treating or preventing a condition such as pain comprising administering to an animal in need thereof an
Tetrazolyl-substituted quinuclidines as substance P antagonists
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Identifikohuni Regjistrohu
TECHNICAL FIELD
This invention relates to novel tetrazolyl-substituted quinuclidine compounds and their pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and the use of such compounds as substance P antagonists.
BACKGROUND ART
Substance P is a naturally
Aprepitant L-proline solvates--compositions and cocrystals
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Identifikohuni Regjistrohu
FIELD OF THE INVENTION
The invention relates to a new aprepritant compositions and crystalline compounds containing aprepitant. More particularly, the invention relates to solvated aprepitant L-proline solvate compositions, aprepitant L-proline solvate cocrystals, therapeutic uses of the aprepitant
Baza e të dhënave më e plotë e bimëve medicinale e mbështetur nga shkenca
- Punon në 55 gjuhë
- Kurime bimore të mbështetura nga shkenca
- Njohja e bimëve nga imazhi
- Harta GPS interaktive - etiketoni bimët në vendndodhje (së shpejti)
- Lexoni botime shkencore në lidhje me kërkimin tuaj
- Kërkoni bimë medicinale nga efektet e tyre
- Organizoni interesat tuaja dhe qëndroni në azhurnim me kërkimet e lajmeve, provat klinike dhe patentat
Shkruani një simptomë ose një sëmundje dhe lexoni në lidhje me barërat që mund të ndihmojnë, shtypni një barishte dhe shikoni sëmundjet dhe simptomat që përdoren kundër.
* I gjithë informacioni bazohet në kërkimin shkencor të botuar
