phytohaemagglutinin/atrophy

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[Increased transfer ribonucleic acid uptake of human leucocytes following gene activation by phytohaemagglutinin and leucemic degeneration (author's transl)].

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Evaluation of immunoregulatory cells in Duchenne muscular dystrophy and spinal muscular atrophy among African and Indian patients.

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Suppressor cells were assayed by numerical and functional tests in Duchenne muscular dystrophy (DMD) and spinal muscular atrophy (SMA) among African and Indian children in order to contribute to an understanding of the pathogenesis of these neurological disorders. Peripheral blood mononuclears (PBM)

Recovery of age-dependent immunological deterioration in Balb/c mice by short-term treatment with L-thyroxine.

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The progressive decline of immune efficiency with advancing age has been investigated in Balb/c mice by measuring the spleen-cell responsiveness to both T- and B-mitogens and the capacity to form plaques after immunization with sheep erythrocytes. While the responsiveness to concanavalin A and

Lectins can reverse the distal intestinal atrophy associated with elemental diets in mice.

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BACKGROUND Elemental diets cause intestinal atrophy and reduced intestinal integrity, which can lead to significant increases in intestinal permeability and bacterial translocation. Recently, several lectins have been shown to have trophic effects on the intestine. OBJECTIVE We examined the effects

Effect of the beta-adrenoceptor agonist clenbuterol and phytohaemagglutinin on growth, protein synthesis and polyamine metabolism of tissues of the rat.

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1. The kidney bean lectin, phytohaemagglutinin (PHA), induced a marked atrophy of skeletal muscle which was evident from the changes in tissue composition (protein, RNA, DNA and polyamine content) and from the reduction in weight and protein synthesis of hind leg muscles of rats fed on kidney

Selective inhibition of immature CD4-CD8+ thymocyte proliferation, but not differentiation, by the thymus atrophy-inducing compound di-n-butyltin dichloride.

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Effects of the thymus atrophy-inducing organotin compound di-n-butyltin dichloride (DBTC) on the differentiation and proliferation of immature rat thymocyte subsets were studied in vivo and in vitro. Incubation of freshly isolated CD4-CD8- or immature CD4-CD8+ (characterized as CD4-CD53-) thymocytes

The effect of phytohaemagglutinin at different dietary concentrations on the growth, body composition and plasma insulin of the rat.

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Young growing rats weighing approximately 83 g were fed on diets containing kidney bean (Phaseolus vulgaris) lectin (phytohaemagglutinin, PHA) in the range of 0-0.45 g/kg body weight for 10 d to ascertain whether there was a minimum dose below which the lectin had no significant effect on body and

Herpes zoster, immunological deterioration and disease progression in HIV-1 infection.

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OBJECTIVE To study the incidence of herpes zoster, the relationship between herpes zoster and immunological markers, and the prognostic value of herpes zoster for progression of HIV disease. METHODS A total of 966 homosexual participants in The Amsterdam Cohort Study were studied. Herpes zoster was

Autologous mixed lymphocyte reaction in newly diagnosed type-1 diabetes.

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The autologous mixed lymphocyte reaction (AMLR) represents activation, proliferation and differentiation of T cells in response to signals from autologous non-T cells. Deteriorations in AMLR have been reported in many autoimmune diseases and in diseases with a derangement in T cell regulatory

Peritoneal macrophages which phagocytose autologous polymorphonuclear leucocytes in guinea-pigs. I: induction by irritants and microorgansisms and inhibition by colchicine.

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In order to examine macrophages phagocytosing polymorphonuclear leucocytes (PMNs) in detail, we established a new method, whereby a large number of PMN-phagocytosing macrophages (PPMs) were easily induced. PPMs were harvested from the peritoneal cavity after thioglycollate medium, oyster glycogen,

[A practical immunologic skin test for piglets].

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At present immune system performance in pigs is decreasing, particularly as a result of environment quality deterioration. Immunological skin tests can also be used to determine the degree of immune system impairment in piglets. A practical immunological skin test was carried out in 48 weaned

Oxidative stress in Chinese patients with Leber's hereditary optic neuropathy.

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The cellular mechanisms of Leber's hereditary optic neuropathy (LHON) are poorly understood and there is little information on the onset of blindness and neurological degeneration. Here we define the relationship between oxidative stress and LHON pathogenicity at the cellular level. Venous blood was

Surface morphology of mitogen-activated human lymphocytes and their derivatives in vitro.

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Human peripheral blood lymphocytes were cultured with phytohaemagglutinin or pokeweed mitogen for various intervals up to 17 days and studied by scanning electron microscopy. Activated lymphocytes in 3 day cultures were large irregular cells characterised mainly by an abundance of very fine

Impaired cellular immunity in kwashiorkor with improvement after therapy.

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Children with kwashiorkor showed a high incidence of deranged cellular immunity as evidenced by impairment of delayed cutaneous hypersensitivity reactions to candida and diphtheria toxoid antigens and of lymphocyte transformation after phytohaemagglutinin stimulation. This may contribute to their

Genetic and environmental variation in immune response of collared flycatcher nestlings.

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This paper aims at partitioning genetic and environmental contribution to the phenotypic variance in nestling immune function measured with the hypersensitivity test after inoculation with phytohaemagglutinin. A cross-fostering experiment with artificial enlargement of some broods was conducted.

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