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tubocurarine/hypersensitivity

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Intradermal histamine releasing effect caused by Org-NC 45. A comparison with pancuronium, metocurine and d-tubocurarine.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
Histamine release caused by Org-NC 45, pancuronium, metocurine and d-tubocurarine was determined by measuring the diameter of the redness and skin induration following the intradermal injection of these drugs. d-Tubocurarine and metocurine caused the largest diameter of redness and induration,

Anaphylactoid response to intravenous tubocurarine.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
A case of severe anaphylactoid reaction to tubocurarine in a 42-year-old female is described. This is particularly notable as there was no history of past allergies or of previous exposure to the drug.

Positive intradermal tests to D-tubocurarine in patients with cholinergic urticaria.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
Patients with cholinergic urticaria exhibit increased hypersensitivity to cholinergic drugs. In the present study, an attempt was made to determine whether these patients would also cross-react to various neuromuscular blocking agents having structures analogous with acetylcholine. The four patients

Developmentally delayed sensitivity of acetylcholine receptor in myotubes of nerve-muscle cocultures from genetically diabetic mouse embryos.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
The neuromuscular junctions of genetically diabetic KK-CAy mice are reported to be hypersensitive to succinylcholine (SuCh) but not to d-tubocurarine (d-TC). Spinal cord-muscle cocultures from normal ddY and diabetic KK-CAy mouse embryos were studied to examine the involvement of genetic factors in

Intradermal histamine release by 3 muscle relaxants.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
The induration and redness caused by intradermal injections of equipotent doses of atracurium, vecuronium and d-tubocurarine were measured in six healthy, male volunteers. Atracurium and d-tubocurarine were almost indistinguishable in their reactions. Vecuronium caused a significantly smaller

Adverse effects of intravenously administered drugs used in anaesthetic practice.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
Adverse effects of intravenous anaesthetic drugs may be divided into local and general effects. The former include venous sequelae ranging from soreness on palpation on the day after the injection to thrombosis of the whole venous system of the arm. Frequency of venous sequelae for water-soluble

Atracurium and vecuronium: two unique neuromuscular blocking agents.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
Atracurium and vecuronium are two new nondepolarizing skeletal muscle relaxants that were developed to overcome the deficiencies seen with currently available agents (tubocurarine, metocurine, pancuronium, and gallamine). Both compounds have unique metabolic profiles, separating them from other

[Histamine release due to ganglion blocking agent and muscle relaxants from rat mast cells].

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
The mechanisms of histamine release due to d-tubocurarine from rat mast cells have long been known to anesthesiologists, such as degranulatory process, Ca++ dependent process and energy coupled process. However, not much is known about histamine release due to some drugs such as trimethaphan and

Diabetic state-induced modifications of succinylcholine binding mode in the microsomal fractions of mouse skeletal muscles.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
The skeletal muscles of alloxan-induced diabetic mice and genetically diabetic KK-CAY mice are hypersensitive to a depolarizing blocker, succinylcholine (SuCh) but not to the competitive antagonist, d-tubocurarine (d-TC). The mechanism by which the action of the depolarizing blocker is modified in

Reaginic antibodies to drugs used in anesthesia.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
Twenty-four patients survived life-threatening clinical anaphylaxis due to anesthesia. In each case the diagnosis of anaphylaxis was confirmed and the responsible drug was found by intradermal testing. To determine whether the reactions were anaphylactic or anaphylactoid, serum from each patient was

Adverse reaction to neuromuscular blockers: frequency, investigation, and epidemiology.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
A survey is presented of neuromuscular drug involvement in 390 clinically severe anaphylactoid reactions (grades II-IV reported to a Sheffield laboratory from 1988 to the end of 1992 from hospitals throughout the UK. Despite advances in patient monitoring and newer drugs, the reporting frequency and

Anaphylaxis to muscle relaxants: cross sensitivity between relaxants.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
Two patients are described who had clinical anaphylaxis due to muscle relaxants. One patient had systemic hypersensitivity and positive intradermal tests to d-tubocurarine and alcuronium. The second had systemic hypersensitivity to d-tubocurarine and positive intradermal tests to d-tubocurarine,

Effects of atropine and neostigmine on receptor interaction at the neuromuscular junction.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
Rats treated chronically with atropine or atropine and neostigmine showed marked alterations in the responsiveness of receptors at the neuromuscular junction. Receptors in the phrenic nerve-hemidiaphragm interacting with d-tubocurarine were unaffected by atropine but exhibited a supersensitivity

Streptozocin-diabetes modifies acetylcholine release from mouse phrenic nerve terminal and presynaptic sensitivity to succinylcholine.

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
Acetylcholine (ACh) release from the motor nerve terminal in the streptozocin-induced diabetic state was studied in mouse phrenic nerve-diaphragm muscle preparations. Electrically evoked release of 3H-ACh from the preparation preloaded with 3H-choline was measured during two consecutive periods of

[Prevention of the unwanted action of hydrocortisone on the growth and development of rat pups with cholinolytic preparations].

Vetëm përdoruesit e regjistruar mund të përkthejnë artikuj
Identifikohuni Regjistrohu
Experiments on young rats have shown that diplacin and d-tubocurarine in doses amounting to 1/15-1/20 of LD50 lower the ability of hydrocortisone to interfere with the physical development of the animals. Metamisyl, metacin, gangleron and benzohexonium have no such properties. In adult rats and
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