Clinical and clinicopathologic observations in induced malignant catarrhal fever of cattle.

In an epizootic of malignant catarrhal fever in 1976/1977 in southern California, 166 cows (17%) died. Blood from one of those cows was used in transmission studies involving 8- to 14-month-old steers. In 17 (74%) of 23 inoculated steers, the disease was reproduced. The clinical signs in 8 of the diseased steers were characterized by an initially mild intestinal form of the disease, which suddenly fulminated and terminated in death within 1 to 3 days. No lesions or only mild oral or ocular lesions were noticed in this group, but in the other steers, such lesions predominated. It was concluded that a subtle form of the disease can terminate in acute fatal indigestion.