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The psychopharmacological activities of Vietnamese ginseng in mice: characterization of its psychomotor, sedative-hypnotic, antistress, anxiolytic, and cognitive effects.

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BACKGROUND Panax vietnamensis Ha et Grushv. or Vietnamese ginseng (VG) is a recently discovered ginseng species. Studies on its chemical constituents have shown that VG is remarkably rich in ginseng saponins, particularly ocotillol saponins. However, the psychopharmacological effects of VG have not

Panax Notoginseng Saponins: A Review of Its Mechanisms of Antidepressant or Anxiolytic Effects and Network Analysis on Phytochemistry and Pharmacology.

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Panax notoginseng (Burk) F. H. Chen, as traditional Chinese medicine, has a long history of high clinical value, such as anti-inflammatory, anti-oxidation, inhibition of platelet aggregation, regulation of blood glucose and blood pressure, inhibition of neuronal apoptosis, and neuronal protection,

Anxiolytic-like effects of ginseng in the elevated plus-maze model: comparison of red ginseng and sun ginseng.

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This study was performed to investigate the anxiolytic-like effects of red ginseng (RG, steamed raw ginseng at 98-100 degrees C) and sun ginseng (SG, heat-processed ginseng at higher temperature) in mice using the elevated plus-maze model. Furthermore, the anxiolytic-like effects of RG and SG were

Anxiolytic activity of Panax ginseng roots: an experimental study.

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The putative anxiolytic activity of the white and red varieties of ginseng, the root of Panax ginseng, was investigated in rats and mice using a number of experimental paradigms of anxiety and compared with that of diazepam. Pilot studies indicated that single-dose administration of ginseng had

Identification of anxiolytic ingredients in ginseng root using the elevated plus-maze test in mice.

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Ginseng root has been widely used for the management of anxiety and emotional instability, but there is little experimental evidence supporting these clinical applications. We pharmacologically identified the anxiolytic components in ginseng root, using the elevated plus-maze test. Male ICR albino

Anxiolytic-like effects of ginsenosides Rg3 and Rh2 from red ginseng in the elevated plus-maze model.

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The anxiolytic-like effects of red ginseng (RG, the steamed root of Panax ginseng, family Araliaceae), its saponin fraction, and its representative constituents, ginsenosides Rg3 and Rh2, were investigated in mice using the elevated plus-maze test. These agents significantly increased the time spent

Anxiolytic effect of saponins from Panax quinquefolium in mice.

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The anxiolytic effect of the saponins from Aniliaeea Panax quinquefolium L. (PQS) was studied in male mice by using a number of experimental paradigms of anxiety and compared with that of the known anxiolytic compound diazepam. Use of the elevated plus-maze test revealed that PQS (50 mg/kg, p.o.)

Chronic oral administration of ginseng extract results in behavioral change but has no effects in mice models of affective and anxiety disorders.

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Ginseng is a popular 'tonic' herb in Chinese traditional medicine with diverse biological activity. The core of ginseng's therapeutic abilities is thought to be its neuroprotective actions in increasing cellular resilience. These actions coincide with novel theories of affective and anxiety

The nootropic properties of ginseng saponin Rb1 are linked to effects on anxiety.

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Previous studies have shown that crude ginseng extracts enhance performance on shock-motivated tasks. Whether such performance enhancements are due to memory-enhancing (nootropic) properties of ginseng, or to other non-specific effects such as an influence on anxiety has not been determined. In the

American Ginseng (Panax quinquefolium L.) as a Source of Bioactive Phytochemicals with Pro-Health Properties.

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Panax quinquefolium L. (American Ginseng, AG) is an herb characteristic for regions of North America and Asia. Due to its beneficial properties it has been extensively investigated for decades. Nowadays, it is one of the most commonly applied medical herbs worldwide. Active compounds of AG

Korean Red Ginseng attenuates anxiety-like behavior during ethanol withdrawal in rats.

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BACKGROUND Korean Red Ginseng (KRG) is known to have antianxiety properties. This study was conducted to investigate the anxiolytic effects of KRG extract (KRGE) during ethanol withdrawal (EW) and the involvement of the mesoamygdaloid dopamine (DA) system in it. METHODS Rats were treated with 3

Fermented ginseng improves the first-night effect in humans.

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OBJECTIVE The goal of this study was to clarify whether ginseng fermented by lactic acid bacteria (fermented ginseng, FG), can improve the first-night effect (FNE) in humans. METHODS Behavioral tests and quantification of mRNA expression related to GABAergic neurotransmission in brain (glutamic acid

Chemical analysis of Panax quinquefolius (North American ginseng): A review.

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Panax quinquefolius (PQ) is one of the best-selling natural health products due to its proposed beneficial anti-aging, anti-cancer, anti-stress, anti-fatigue, and anxiolytic effects. In recent years, the quality of PQ has received considerable attention. Sensitive and accurate methods for

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