Asthma / otok

Peptide compositions and methods for treating lung injury, asthma, anaphylaxis, angioedema, systemic vascular permeability syndromes, and nasal congestion

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FIELD OF THE INVENTION The present invention relates to peptides for treating lung injury, including inflammation-mediated vascular leakage and the development of edema. The present invention also relates to treating asthma, anaphylaxis, angioedema, systemic vascular permeability syndromes, and

Peptide compositions and methods for treating lung injury, asthma, anaphylaxis, angioedema, systemic vascular permeability syndromes, and nasal congestion

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Пријави се / Пријави се

FIELD OF THE INVENTION The present invention relates to peptides for treating lung injury, including inflammation-mediated vascular leakage and the development of edema. The present invention also relates to treating asthma, anaphylaxis, angioedema, systemic vascular permeability syndromes, and

1,3-diaryl cyclopentanes and derivatives thereof as PAF antagonists

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BACKGROUND OF THE INVENTION Platelet-activating factor (PAF) has recently been identified as an acetyl glyceryl ether phosphorylcholine (AGEPC), i.e., 1-O-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (Hanahan D. J. et al., J. Biol. Chem. 255:5514, 1980). Even before its chemical

1,3-diaryl cyclopentanes and derivatives thereof as PAF antagonists

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BACKGROUND OF THE INVENTION Platelet-activating factor (PAF) has recently been identified as an acetyl glyceryl ether phosphorylcholine (AGEPC), i.e., 1-0-hexadecyl/octadecyl-2-acetyl-sn-glyceryl-3-phosphorycholine (Hanahan D. J., et al., J. Biol. Chem. 255:5514, 1980). Even before its chemical

Opioid compounds and methods for using same

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates generally to diarylmethyl piperazine compounds having utility in medical therapy especially as receptor-binding species, e.g., as conjugates in agonist/antagonist pairs for verifying/assaying receptor and neurotransmitter

Opioid compounds

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates generally to diarylmethyl piperazine compounds having utility in medical therapy especially as receptor-binding species, e.g., as conjugates in agonist/antagonist pairs for verifying/assaying receptor and neurotransmitter

Opioid compounds and methods for making therefor

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BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates generally to diarylmethyl piperazine compounds having utility in medical therapy especially as receptor-binding species, e.g., as conjugates in agonist/antagonist pairs for verifying/assaying receptor and neurotransmitter

Pyrazolopyridine compound and processes for preparation thereof

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The present invention relates to novel pyrazolopyridine compound and a pharmaceutically acceptable salt thereof. More particularly, it relates to novel pyrazolopyridine compound and a pharmaceutically acceptable salt thereof, which are adenosine antagonists and possess various pharmaceutical actions

Indolylmaleimide derivatives

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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Indolylmaleimide derivatives

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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Indolylmaleimide derivatives

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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them. More particularly the present invention provides a compound of formula I ##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b

Chimeric and humanized anti-histone antibodies

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SEQUENCE LISTING The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1_SL.txt and is 71,342 bytes in size. FIELD OF THE

Chimeric and humanized anti-histone antibodies

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FIELD OF THE INVENTION The invention relates to compositions and methods of use of anti-histone antibodies or antigen-binding fragments thereof. In particular embodiments, the antibodies bind to human histones H2B, H3 or H4. The anti-histone antibodies are of use for diagnosis and/or therapy of a

Nucleic acids encoding chimeric and humanized anti-histone antibodies

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SEQUENCE LISTING The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1_SL.txt and is 71,342 bytes in size. FIELD OF THE

Methods for treating thrombosis using chimeric and humanized anti-histone antibodies

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SEQUENCE LISTING The instant application contains a Sequence Listing which has been submitted in ASCII format via EFS-Web and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Feb. 10, 2014, is named IMM342US1_SL.txt and is 71,342 bytes in size. FIELD OF THE

asthma/otok

Peptide compositions and methods for treating lung injury, asthma, anaphylaxis, angioedema, systemic vascular permeability syndromes, and nasal congestion

Peptide compositions and methods for treating lung injury, asthma, anaphylaxis, angioedema, systemic vascular permeability syndromes, and nasal congestion

1,3-diaryl cyclopentanes and derivatives thereof as PAF antagonists

1,3-diaryl cyclopentanes and derivatives thereof as PAF antagonists

Opioid compounds and methods for using same

Opioid compounds

Opioid compounds and methods for making therefor

Pyrazolopyridine compound and processes for preparation thereof

Indolylmaleimide derivatives

Indolylmaleimide derivatives

Indolylmaleimide derivatives

Chimeric and humanized anti-histone antibodies

Chimeric and humanized anti-histone antibodies

Nucleic acids encoding chimeric and humanized anti-histone antibodies

Methods for treating thrombosis using chimeric and humanized anti-histone antibodies

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