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atropine/атрофија

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Страна 1 од 196 резултати

Atropine sensitivity of the rat urinary bladder during nerve degeneration.

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The pressure response of the rat urinary bladder to electrical stimulation of the pelvic nerve at a low stimulation frequency was found to be almost completely atropine resistant. However, the response to stimulation of the degenerating pelvic nerve 20-30 h after section of the nerve

Simple high-performance liquid chromatographic method for assessing the deterioration of atropine-oxime mixtures employed as antidotes in the treatment of nerve agent poisoning.

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A set of reversed-phase HPLC conditions for determining the degradation of atropine and the oxime (pralidoxime, obidoxime, or HI-6) in autoinjectors designed for use against nerve agent poisoning is described. The assay conditions for atropine do not require its prior separation from the large molar

Parasympathetic degeneration secretion of saliva in rats.

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In rats under chloralose anaethesia saliva was found to flow from the submandibular and parotid glands previously subjected to (partial) postganglionic parasympathetic denervation. Secretion started in the submandibular glands 8.8-11.8 hours, and in the parotid glands 14.0-12.6 hours after the

Comparison of the effects of atropine and glycopyrrolate on pulmonary mechanics in patients undergoing fiberoptic bronchoscopy.

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The effects of atropine and glycopyrrolate on forced vital capacity (FVC), forced expired volume in one second (FEV1), the FEV1/FVC ratio, and peak expiratory flow (PFL) were compared in 44 patients undergoing fiberoptic bronchoscopy under general anesthesia. Both anticholinergic agents improved

A rat model of nerve agent exposure applicable to the pediatric population: The anticonvulsant efficacies of atropine and GluK1 antagonists.

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Inhibition of acetylcholinesterase (AChE) after nerve agent exposure induces status epilepticus (SE), which causes brain damage or death. The development of countermeasures appropriate for the pediatric population requires testing of anticonvulsant treatments in immature animals. In the present

Comments on the atropine resistance of the neurogenic contractile response of the rat detrusor muscle.

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The resistance to atropine or scopolamine of the neurogenic contractile response to field stimulation of intramural nerves of the rat detrusor was studied during the early phase of Wallerian degeneration in vitro and in vivo. The neurogenic contractile response to low frequency stimulation of

Protection by Neostigmine and Atropine Against Brain and Liver Injury Induced by Acute Malathion Exposure.

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We examined the effect of treatment with neostigmine alone or with atropine on brain oxidative stress and on brain and liver tissue damage following acute malathion toxicity. Rats were intraperitoneally treated with malathion 150 mg/kg along with neostigmine (200 or 400 μg/kg) or neostigmine (200

Dobutamine improves afterload-induced deterioration of mechanical efficiency toward maximal.

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We studied the effect of increased afterload on the ratios of O2 consumption (VO2) to external work (EW), VO2 to the systolic pressure-volume area (PVA), and PVA to EW at control state and with dobutamine in the left ventricles of open-chest dogs. Left ventricular volume was measured with a

Activation of muscarinic receptors protects against retinal neurons damage and optic nerve degeneration in vitro and in vivo models.

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OBJECTIVE Muscarinic acetylcholine receptor agonist pilocarpine reduces intraocular pressure (IOP) of glaucoma mainly by stimulating ciliary muscle contraction and then increasing aqueous outflow. It is of our great interest to know whether pilocarpine has the additional properties of retinal

The effects of fiberoptic bronchoscopy with and without atropine premedication on pulmonary function in humans.

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Pulmonary function studies, including arterial blood gas analysis, were performed in 21 patients undergoing fiberoptic bronchoscopy. Eight received premedication with atropine and 13 did not. In the atropine-treated group there was no significant deterioration in pulmonary function immediately after

Effects of atropine sulfate on rat harderian glands: correlation between morphological changes and porphyrin levels.

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We examined the correlation between histopathological changes and porphyrin levels in the Harderian glands of male rats after treatment with atropine sulfate. After a single administration of atropine sulfate (250 mg/kg/day), the porphyrin levels in the Harderian glands gradually increased,

Treatment of tabun poisoned guinea-pigs with atropine, HLö 7 or HI 6: effect on respiratory and circulatory function.

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The oxime HI 6 (in combination with atropine) is considered to be an effective antidote in soman intoxication but was shown to be less effective in tabun poisoning. In contrast to HI 6, first in vitro studies with HLö 7 demonstrated a reasonable reactivating potency at acetylcholinesterase (AChE)

Histopathologic effects of the single intramuscular injection of ketamine, atropine and midazolam in a rat model.

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Ketamine and atropine are often combined in a single syringe for im injection for pediatric conscious sedation; however, the effort of adding midazolam to this combination has not been studied. We investigated the single im injection of ketamine, atropine and midazolam (KAM) to determine if it

Comparison of the effects of atropine and glycopyrrolate on cognitive function following general anaesthesia.

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Tests of orientation, concentration and short-term visual memory were used to assess 72 patients 1 day before, and 2 days after, elective major surgery. Patients were premedicated with papaveretum and either atropine or glycopyrrolate, before receiving a standard general anaesthetic. Those who had

Atropine and cerebral ischemic injury in the Mongolian gerbil.

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1. Cerebral ischemia of 5 min duration was induced in unanesthetized gerbils by bilateral occlusion of the carotid arteries. 2. The extent of cerebral damage was assessed by the elevation of motor activity in comparison with control animals and by a histological assessment of the extent of neuronal
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