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Страна 1 од 25 резултати
Population at Risk of Malignant Hyperthermia: Ambispective Cohort.
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Malignant hyperthermia (MH) is a pharmacogenetic disease that manifests itself as a hypermetabolic response of skeletal musculature, in genetically susceptible patients, with the inhalation of volatile halogenated anesthetics, depolarizing neuromuscular relaxants such and, rarely, physical stressors
Early Caffeine and LISA Compared to Caffeine and CPAP in Preterm Infants
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After 5 minutes of life, consented infants that are assessed by a provider as clinically stable (i.e. HR> 100 bpm) and spontaneously breathing on CPAP will be randomized by computer generated randomization cards placed in opaque envelopes.
For infants not consented prior to birth, after 5 minutes of
Acute Effects of Beet Extract on Autonomic and Cardiovascular Recovery After Exercise
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An anamnesis of the participants will be made before the research. Essential information such as name, gender, age, height, BMI will be collected. Anthropometric measurements will be acquired according to the recommendations. Volunteers will be properly informed about the procedures and objectives
Dark Chocolate and Exercise Performance in Hypoxia
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Dark chocolate is rich in flavonoids, bioactive micronutrients that increase the bioavailability of nitric oxide as well as decrease the rate in which nitric oxide is removed from the body. Through increasing the bioavailability of nitric oxide (NO) to bodily tissues, the tissues are better able to
Evaluation of Coffee Therapy for Improvement of Renal Oxygenation
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Comparison of Automated Oxygen Control With and Without Automated Pressure Control in Preterm Ventilated Infants.
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Supplemental oxygen remains by far the most commonly used 'drug' in neonatal intensive care units. The goal of oxygen therapy is to maintain normal oxygenation while minimizing hyperoxaemia and hypoxemia. Preterm infants are particularly vulnerable to oxygen toxicity and oxidative stress leading to
The Beneficial Effects of Pomegranate on Hearing of Patients Without Hemodialysis
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Pomegranate has anti-oxidative capacity. It might reduce symptoms of Alzheimer's disease, Drug-induced hepatitis, and might prevent deterioration of cardiovascular diseases and cancer progression. But, the beneficial effects of pomegranate on hearing impairment was still unclear.
This study aimed to
AT1R Blockade and Periodic Breathing During Sleep in Hypoxia
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Objective: To determine the effects of angiotensin-II, type-I receptor (AT1R) blockade on the relationship between ventilatory control and sleep disordered breathing (SDB) following a night of hypoxic sleep in healthy humans.
Justification: Ventilatory adaptation to hypoxia is one of two major
Intermittent Hypoxia and Caffeine in Infants Born Preterm
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Acute morbidities can contribute to adverse neurodevelopment outcomes in preterm infants born at ≤30 wks gestation, but neural damage occurring after resolution of acute morbidities may be more subtle and related to cycles of inflammation and repair in the developing brain. One possible contributor
Effect of an H1 Receptor Antagonist on Exercise Performance in Hypoxia
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This study seeks to determine whether a simple, single intervention of Cetirizine / Zyrtec® use can improve exercise performance of active individuals when acutely exposed to altitude. For this project, healthy subjects will perform steady state and progressive work rate exercise, endurance
NIPPV Versus Bi-level Nasal Continuous Positive Airway Pressure Following Extubation
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In this study , mechanically ventilated preterm infants with birthweight ≤1250 g will screen for eligibility. Infants with major congenital malformations, neuromuscular disease and lack of parental consent were excluded. Enrolled infants will randomize into two study groups (NIPPV group and BIPAP
Intermittent Hypoxemia and Acute Kidney Injury Study (IHAKI Study)
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BACKGROUND:
Preterm birth is a major health care concern and although survival of premature infants has improved, the incidence of neonatal morbidities has slightly decreased especially in cases of extreme prematurity. Apnea of prematurity (immature respiratory control) is a major complication in
Non-invasive Intervention for Apnea of Prematurity
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Aim: To study the effect of limb proprioceptive stimulation using a vibratory device on apneic events, intermittent hypoxic episodes and bradycardias in a premature infant with apnea of prematurity.
The objective is to provide support and to assist impaired ventilation and oxygenation in apnea of
Endurance Performance at Altitude
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1. Purpose
The purpose of this research proposal is to evaluate the role of hypoxic pulmonary vasoconstriction (HPV) and the formation of arteriovenous anastomoses (shunts) in hypoxia and their effect on endurance exercise performance. The pulmonary vasodilator sildenafil will be used to reverse the
the Influence of Remote Ischemic Preconditioning on Inflammation During Human Endotoxemia
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Although the immune system is essential to survival, a variety of diseases originate from inappropriate or excessive activation of the immune response. Examples include a wide range of auto-inflammatory disease, infectious diseases such as sepsis, but also after major surgery like cardiac artery
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