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Directly compressible medicated chewing gum formulation for quick relief from common cold.

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BACKGROUND Common cold is the most frequently recurring disease in the world and is a leading cause of doctor visits and missed days from school and work. Cold reliever medicated chewing gum (MCG) will be a definitive patient acceptable solution for this condition. Anti-allergic, cetirizine (CTZ) is

Which anti-histamines dermatological specialists select in their therapies for common skin diseases? A practical analysis from multiple clinics.

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In the treatment of skin diseases, antihistamines and antiallergic agents are among the most frequently used oral medications, and are available as a wide variety of products. We investigated what criteria dermatological specialists use to select antihistamines and antiallergic agents, as well as

[The antiallergic effect of Balkis. A rhino-manometric study].

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The antiallergic and decongestive effects of the common cold preparation Balkis was tested by rhinomanometry in human volunteers usually suffering from allergic rhinitis after oral treatment. The nasal irritation in these patients was induced by administration of the specific allergen. This kind of

In vitro studies on the mechanism of action of a new antiallergic, Ro 21-7634.

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The effects of Ro 21-7634 and disodium cromoglycate (cromoglycate) on the in vitro release of mediators of anaphylaxis from rat peritoneal cells and guinea pig lung tissue were compared. Ro 21-7634 was 25 fold more potent than cromoglycate as an inhibitor of antigen-induced histamine release from

N-(3',4'-dimethoxycinnamoyl)anthranillic acid, an antiallergic compound, induced eosinophilic cystitis.

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Eosinophilic cystitis developed in an asthmatic patient after therapy with the antiasthmatic agent, Tranilast. The progress of this patient and the histopathologic findings of bladder biopsy specimens are reported. A review of recent publications on the possible causative correlations is presented.

[Rhinitis therapy. Experiences with triprolidine hydrochloride/pseudoephedrin hydrochloride, a decongestive and antiallergic therapeutic agent].

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63 patients were treated with the combination of pseudoephedrine hydrochloride and triprolidine hydrochloride (Actifed). Indications were infectious, allergic and vasomotoric rhinitis. The 63 patients divided in 32 children in the age of 2 to 12 years and 31 adults in the age of 14 to 56 years. The

The Use of Antiallergic and Antiasthmatic Drugs in Viral Infections of the Upper Respiratory Tract.

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Despite their frequency, upper respiratory tract infections (URTIs) constitute an area with few, if any, effective treatment remedies. Asthma and airway allergies share similar pathogenetic mechanisms to URTIs and it is not surprising, therefore, that agents used to treat allergic disorders have

Antiallergic properties of SQ 13,847, an orally effective agent. II. Activity in vitro.

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SQ 13,847, a pyrazolo[1,5-c]quinazoline with potent oral antiallergic activity in the rat, was compared with its principal oxidative metabolite, SQ 12,903, for ability to block the release of histamine from the rat mast cell in vitro. SQ 12,903, at concentrations in the range of 0.3 to 2 micrometer,

Potential targets for anti-inflammatory and anti-allergic activities of marine algae: an overview.

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The inflammatory and allergic diseases are among the most common diseases all over the world. The prevalence, severity, and complexity of these diseases are rapidly rising and considerably adding to the burden of healthcare costs. Although the synthetic and combinatorial chemistry have given rise to

Structure-activity relationships for non-congeneric structures. Application of substructural balance method for antiallergic activity.

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This paper presents a new research method of structure-activity relationships (SAR) based on the concept of substructural balance. By using antiallergic activity (PCA, rat, iv) of a non-congeneric set of 267 structures, the structural feature of active group is expressed in terms of substructural

[In vitro effects of antiallergic eyedrops on complement activation induced by particulate matter].

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BACKGROUND Recent decades have been marked by an increasing number of patients suffering from ocular allergic-like symptoms without being associated with an increase in IgE levels. These symptoms include heaviness of the lid, foreign body sensation, burning, stinging and photophobia. Both

Inhibitory effect of anti-allergic agent NCO-650 on histamine release induced by various secretagogues.

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Histamine release from rat peritoneal mast cells induced by antigen and anti-IgE was essentially complete within 2 min and 3 min, respectively, but that due to Concanavalin A (Con A) was complete only within 9 min. An anti-allergic agent NCO-650 [trans-4-Guanidinomethylcyclohexanecarboxylic acid

In vitro anti-allergic activities of a newly concocted traditional Chinese medicine--the wheeze-relief formula.

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Asthma is one of the most common chronic diseases worldwide. Western medications such as glucocorticoids are effective therapeutic agents but may be associated with side effects. Traditional Chinese medicine (TCM) has been used for treating allergic diseases with observable clinical benefits. The

Synthesis of Daidzein Glycosides, α-Tocopherol Glycosides, Hesperetin Glycosides by Bioconversion and Their Potential for Anti-Allergic Functional-Foods and Cosmetics.

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Daidzein is a common isoflavone, having multiple biological effects such as anti-inflammation, anti-allergy, and anti-aging. α-Tocopherol is the tocopherol isoform with the highest vitamin E activity including anti-allergic activity and anti-cancer activity. Hesperetin is a flavone, which shows

A Sensitive and Rapid UPLC-MS/MS Method for Determination of Monosaccharides and Anti-Allergic Effect of the Polysaccharides Extracted from Saposhnikoviae Radix.

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Background: Allergic disease is a common clinical disease. Natural products provide an important source for a wide range of potential anti-allergic agents. This study was designed to evaluate the anti-allergic activities of the water-soluble polysaccharides extracted and purified from Saposhnikoviae

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