Dermatitis / tyrosine

Homopiperazine derivatives as protein tyrosine kinase inhibitors and pharmaceutical use thereof

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FIELD OF THE INVENTION This invention relates to compounds which are inhibitors of protein tyrosine kinases, such as the Janus kinases, and to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases comprising administering to a

Sulfamide piperazine derivatives as protein tyrosine kinase inhibitors and pharmaceutical use therof

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FIELD OF THE INVENTION This invention relates to compounds which are inhibitors of protein tyrosine kinases, such as the Janus kinases, and to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases comprising administering to a

RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions

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FIELD OF THE INVENTION The present invention relates to the field of interfering RNA compositions for silencing spleen tyrosine kinase (Syk) and for treatment of a Syk-related inflammatory condition. Such conditions include allergic conjunctivitis, ocular inflammation, dermatitis, rhinitis, asthma,

RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions

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FIELD OF THE INVENTION The present invention relates to the field of interfering RNA compositions for silencing spleen tyrosine kinase (Syk) and for treatment of a Syk-related inflammatory condition. Such conditions include allergic conjunctivitis, ocular inflammation, dermatitis, rhinitis, asthma,

RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions

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FIELD OF THE INVENTION The present invention relates to the field of interfering RNA compositions for silencing spleen tyrosine kinase (Syk) and for treatment of a Syk-related inflammatory condition. Such conditions include allergic conjunctivitis, ocular inflammation, dermatitis, rhinitis, asthma,

Heterocyclic compounds as JAK receptor and protein tyrosine kinase inhibitors

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FIELD OF THE INVENTION This invention relates to compounds which are inhibitors of protein tyrosine kinases, such as the Janus kinases, and to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases comprising administering to a

Pyrimidine-5-carboxamides as spleen tyrosine kinase inhibitors

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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not applicable. THE NAMES OF THE PARTIES TO A JOINT RESEARCH AGREEMENT Not applicable. INCORPORATION-BY-REFERENCE OF MATERIAL SUBMITTED ON A COMPACT DISC Not applicable. BACKGROUND Allergic inflammatory conditions are largely the

Substituted pyrimidine-5-carboxamides as spleen tyrosine kinase inhibitors

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STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT Not applicable. THE NAMES OF THE PARTIES TO A JOINT RESEARCH AGREEMENT Not applicable. INCORPORATION-BY-REFERENCE OF MATERIAL SUBMITTED ON A COMPACT DISC Not applicable. BACKGROUND Allergic inflammatory conditions are largely the

Amino substituted pyrazines as inhibitors or protein kinases

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TECHNICAL FIELD The present invention relates to pyrazine compounds that act as inhibitors of protein kinases, specially the Fms-like tyrosine kinase 3 (FLT3). The invention further relates to pharmaceutical compositions comprising these compounds, and to the use of the compounds for the preparation

Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues

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BACKGROUND OF THE INVENTION The stilbenes isolated from Photorhabdus species bacteria are known to have antibiotic activity (Paul et al. Journal of Chemical Ecology, 7: 589-597 (1981), and Hu et al., Canadian Journal of Microbiology. 44: 1072-1077 (1998). However, these compounds have not been shown

Monocyclic-7H-pyrrolo[2,3-d]pyrimidine compounds, compositions, and methods of use

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BACKGROUND OF THE INVENTION The present invention relates to pyrrolo[2,3-d]pyrimidine compounds which are inhibitors of protein tyrosine kinases, such as the enzyme Janus Kinase 3 (hereinafter also referred to as JAK3) and as such are useful therapy as immunosuppressive agents for organ transplants,

Pyrrolo[2,3-d]pyrimidine compounds

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BACKGROUND OF THE INVENTION The present invention relates to pyrrolo[2,3-d]pyrimidine compounds which are inhibitors of protein tyrosine kinases, such as the enzyme Janus Kinase 3 (hereinafter also referred to as JAK3) and as such are useful therapy as immunosuppressive agents for organ transplants,

Pyrrolo[2,3-d]pyrimidine compounds

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BACKGROUND OF THE INVENTION The present invention relates to pyrrolo[2,3-d]pyrimidine compounds which are inhibitors of protein tyrosine kinases, such as the enzyme Janus Kinase 3 (hereinafter also referred to as JAK3) and as such are useful therapy as immunosuppressive agents for organ transplants,

Pyrrolo [2,3-D] pyrimidine compounds

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BACKGROUND OF THE INVENTION The present invention relates to pyrrolo[2,3-d]pyrimidine compounds which are inhibitors of protein tyrosine kinases, such as the enzyme Janus Kinase 3 (hereinafter also referred to as JAK3) and as such are useful therapy as immunosuppressive agents for organ transplants,

Pyrrolo[2,3-d]pyrimidine compounds

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Пријави се / Пријави се

BACKGROUND OF THE INVENTION The present invention relates to pyrrolo[2,3-d]pyrimidine compounds which are inhibitors of protein tyrosine kinases, such as the enzyme Janus Kinase 3 (hereinafter also referred to as JAK3) and as such are useful therapy as immunosuppressive agents for organ transplants,

dermatitis/tyrosine

Homopiperazine derivatives as protein tyrosine kinase inhibitors and pharmaceutical use thereof

Sulfamide piperazine derivatives as protein tyrosine kinase inhibitors and pharmaceutical use therof

RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions

RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions

RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions

Heterocyclic compounds as JAK receptor and protein tyrosine kinase inhibitors

Pyrimidine-5-carboxamides as spleen tyrosine kinase inhibitors

Substituted pyrimidine-5-carboxamides as spleen tyrosine kinase inhibitors

Amino substituted pyrazines as inhibitors or protein kinases

Anti-inflammatory and psoriasis treatment and protein kinase inhibition by hydroxy stilbenes and novel stilbene derivatives and analogues

Monocyclic-7H-pyrrolo[2,3-d]pyrimidine compounds, compositions, and methods of use

Pyrrolo[2,3-d]pyrimidine compounds

Pyrrolo[2,3-d]pyrimidine compounds

Pyrrolo [2,3-D] pyrimidine compounds

Pyrrolo[2,3-d]pyrimidine compounds

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