13 резултати
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to new use of Lactobacillus isolates, in particular, to the technical field of treatments for type II diabetes.
2. Description of the Prior Art
Diabetes Mellitus is a metabolism disease of many pathogens. It is a
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to triglyceride reducing agents for use in the human body, and, more particularly, a flavour compound for prevention and treatment of hyperlipidemia (hypertriglyceridemia).
2. Description of Related Art
The
PRIORITY
The present application claims the benefit of Indian Provisional Patent Application No. 1853/CHE/2012 filed on 10 May 2012 and the International Application No. PCT/IB2013/051596 filed on 28 Feb. 2013, the entire disclosure of which is relied on for all purposes and is incorporated into
FIELD OF THE INVENTION
This invention relates to compounds which are dialkyl ethers having terminal carboxy or tetrazole groups. The compounds are useful for lowering certain plasma lipids in animals, including Lp(a), triglycerides, VLDL-cholesterol, and LDL-cholesterol, and elevating others such as
FIELD OF THE INVENTION
This invention relates to compounds which are dialkyl ethers having terminal carboxy or tetrazole groups. The compounds are useful for lowering certain plasma lipids in animals, including Lp(a), triglycerides, VLDL-cholesterol, and LDL-cholesterol, and elevating others such as
BACKGROUND OF THE INVENTION
Vascular diseases such as coronary heart disease, stroke, restenosis, and peripheral vascular disease, remain the leading cause of death and disability throughout the world. About 1.5 million people die each year in the US alone from myocardial infarction resulting from
FIELD OF THE INVENTION
This invention relates to compounds which are dialkyl ethers having terminal carboxy or tetrazole groups. The compounds are useful for lowering certain plasma lipids in animals, including Lp(a), triglycerides, VLDL-cholesterol, and LDL-cholesterol, and elevating others such as
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is the U.S. national stage filing under 35 U.S.C. .sctn.371 of international application PCT/KR2010/008944, filed Dec. 14, 2010, which claims benefit of Korean Patent Application No. 10-2010-0004901, filed Jan. 19, 2010.
FIELD OF THE
FIELD OF THE INVENTION
The present invention relates to metabolites of trans-clomiphene in substantially pure form, pharmaceutical compositions comprising same and methods for treating various hormone-dependent disorders.
BACKGROUND
Clomiphene is a selective estrogen receptor modulator related to
BRIEF DESCRIPTION OF THE INVENTION
The present invention relates to compounds that acts as G-protein coupled receptor 120 (GPR120) and/or 40 (GPR40) agonists, pharmaceutical compositions containing them and their use in the treatment of diseases or disorders modulated by said GPRs such as diabetes
CROSS-REFERENCE TO RELATED APPLICATIONS
This application is the U.S. national stage filing under 35 U.S.C. .sctn.371 of international application PCT/KR2009/007905, filed Dec. 29, 2009, which claims benefit of Korean Patent Application 10-2009-0022937, filed Mar. 18, 2009.
TECHNICAL FIELD
The
REFERENCE TO A "SEQUENCE LISTING," A TABLE, OR A COMPUTER PROGRAM LISTING APPENDIX SUBMITTED ON A COMPACT DISK
Not Applicable
BACKGROUND OF THE INVENTION
In 2003, the International Diabetes Federation estimated that there were 194 million people worldwide with diabetes. Of these, some 16 million
BACKGROUND
Oxidative stress and inflammation are implicated in the pathogenesis of metabolic diseases, diabetes, obesity, dyslipidemia and their associated cardiovascular complications. For example, oxidative stress is a common pathogenic factor leading to insulin resistance, beta-cell dysfunction,