5 резултати
OBJECTIVE
A high consumption of fructose leads not only to peripheral changes in insulin sensitivity and vascular function, but also to central changes in several brain regions. Given the role of the endogenous cannabinoid system in the control of energy intake, we undertook a pilot study to
OBJECTIVE
To investigate the effect of metabolic syndrome on the bladder cannabinoid receptors 1 and 2 (CB1/CB2) expression and function in the fructose-fed rats (FR).
METHODS
Adult male Sprague-Dawley rats were divided into two groups: (i) Control rats fed with normal chow; and (ii) Rats fed with
Chronic oral treatment of young adult male Fischer rats with delta 9-tetrahydrocannabinol (THC), 1, 5 and 25 mg kg-1 day-1, or crude marihuana extract (CME), 3, 15 and 75 mg kg-1 day-1, reduced body weight gain by about 50-80% at the high CME or THC dose and was correlated with decreased food
OBJECTIVE
This study aimed to determine the cellular distribution of islet cannabinoid receptors (CBs) and their involvement in the development of metabolic and hormonal changes in rats fed a fructose-rich diet (F).
METHODS
In normal rat islets, we determined CBs (immunofluorescence and
Cannabis sativa trichomes are glandular structures predominantly responsible for the biosynthesis of cannabinoids, the biologically active compounds unique to this plant. To the best of our knowledge, most metabolomic works on C. sativa that have been reported previously focused their investigations