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12 резултати
Thieno[3,2-b]pyridine derivatives
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FIELD OF THE INVENTION
The present invention relates to novel thieno[3,2-b]pyridine derivative useful as pharmaceutical agents. More specifically, the present invention relates to novel thieno[3,2-b]pyridine derivatives, the pharmaceutically acceptable salts thereof and the solvates thereof,
Deuterium-enriched pyridinonecarboxamides and derivatives
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SUMMARY OF THE INVENTION
The present invention is concerned with deuterium-enriched pyridinone carboxamides and derivatives thereof of formula I,
##STR00002##
Wherein, R.sub.1 and R.sub.2 are independently, H, D (deuterium with enrichment of 1%-100%), F, Cl, CD.sub.3 (methyl-d.sub.3),
Deuterium-enriched pyridinonecarboxamides and derivatives
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SUMMARY OF THE INVENTION
The present invention is concerned with deuterium-enriched pyridinonecarboxamides and derivatives thereof of formula 1,
##STR00002## Wherein, R.sub.1 and R.sub.2 are independently, H, D (deuterium with enrichment of 1%-100%), F, Cl, CD.sub.3 (methyl-d.sub.3),
Material and methods for the treatment of gastro-intestinal disorders
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FIELD
The present disclosure relates to bulk compositions and pharmaceutical compositions comprising a trihydrate form of (3S, 4R, 3'R)-6-[4-(4-amino-5-chloro-2-methoxy-benzoylamino)-3-methoxy-piperidin-1- -yl]-hexanoic acid 1-azabicyclo[2.2.2]oct-3'-yl ester di-hydrochloride salt, and methods of
Thienopyridinone compounds and methods of treatment
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FIELD OF THE INVENTION
The invention generally relates to the field of serotonin (5-hydroxytryptamine, or 5-HT) receptor modulators, e.g., agonists, partial agonists, inverse agonists, antagonists, and more particularly to new thienopyridinone compounds, the synthesis and use of these compounds and
Thienopyridinone compounds and methods of treatment
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FIELD OF THE INVENTION
The invention generally relates to the field of serotonin (5-hydroxytryptamine, or 5-HT) receptor modulators, e.g., agonists, partial agonists, inverse agonists, antagonists, and more particularly to new thienopyridinone compounds, the synthesis and use of these compounds and
Synthesis of thienopyridinone compounds and related intermediates
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FIELD OF THE INVENTION
The invention generally relates to the field of serotonin (5-hydroxytryptamine, or 5-HT) receptor modulators, e.g., agonists, partial agonists, inverse agonists, antagonists, and more particularly to new thienopyridinone compounds, the synthesis and use of these compounds and
Aromatic amides of heterocyclic compounds and therapeutic compositions containing same
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SUMMARY OF THE INVENTION
According to our invention, in its broadest aspect, we provide a compound corresponding to the general formula (I): ##STR1## in which: R is a lower (C.sub.1 -C.sub.6) alkoxy or alkenoxy;
R.sub.1 and R.sub.2, which may be the same or different, are selected from hydrogen,
Anti-psychotic (cycloalkenylalkylpiperidino) benzamides
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SUMMARY OF THE INVENTION
According to one aspect of our invention, we provide compounds of the general formula ##STR1## wherein R represents a lower alkoxy or lower alkenyloxy group; R.sup.1 and R.sup.2, which may be the same or different, each represent a hydrogen or halogen atom, or a
Substituted benzoylaminothiazole derivatives and drugs containing the same
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TECHNICAL FIELD
The present invention relates to a novel benzoylaminothiazole derivative having improving effects on the dysmotility in the gastrointestinal tract, a medicament containing the derivative and an intermediate for preparing said compound.
BACKGROUND ART
As a therapeutic agent for
Cinnoline-3-carboxylic acid derivatives
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FIELD OF THE INVENTION
This invention relates to a cinnoline derivative which is pharmaceutically useful as an antagonist against serotonin 5-HT.sub.3 receptor, its pharmaceutically acceptable salts, its N-oxide derivatives or solvates thereof, and pharmaceutical compositions containing the
Cinnoline-3-carboxylic acid derivatives
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FIELD OF THE INVENTION
This invention relates to a cinnoline derivative which is pharmaceutically useful as an antagonist against serotonin 5-HT.sub.3 receptor, its pharmaceutically acceptable salts, its N-oxide derivatives or solvates thereof, and pharmaceutical compositions containing the
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